ArticleBMC infectious diseases2019
Epidemiological characteristics, clinical manifestations and laboratory findings in 850 patients with brucellosis in Heilongjiang Province, China.
Article in BMC infectious diseases, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
40 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Research hotspots and development trends ofFrontiers in microbiology · 2025Pooled it
- Epidemiological analysis of infectious disease in border port areas of Heilongjiang Province, 2014-2023.BMC public health · 2026Article
- Establishment of a rapid Brucella detection method based on MCDA-CRISPR dual signal amplification system for reducing transfusion-transmitted diseases.Scientific reports · 2026Article
- Retrospective Analysis of Epidemiologic, Clinical, and Laboratory Findings of Patients Diagnosed with Brucellosis and Review of the Literature.Infectious diseases & clinical microbiology · 2026Article
- Brucellosis mimicking upper gastrointestinal symptoms: A diagnostic challenge-A rare case report.IDCases · 2026Article
- Integrated clinical and PBMC transcriptomic profiling identifies lipid metabolism-related candidate signatures associated with chronic brucellosis.Frontiers in cellular and infection microbiology · 2026Article
- Clinical epidemiological characteristics and treatment outcomes of Brucella spondylitis in Ningxia, China: a 12‑year single‑center retrospective study.BMC infectious diseases · 2025Article
- Development and validation of a clinico-biological score for Brucella spondylitis: a two-center study.BMC infectious diseases · 2025Article
- Anterior debridement, reconstruction, and fusion for cervical brucellosis spondylitis with epidural abscess: a single-center experience of 30 patients.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2025Article
- Brucellosis novel multi-epitope vaccine design based on in silico analysis focusing on Brucella abortus.BMC immunology · 2025Article
- Antimicrobial resistant Brucella spp. prevail in raw milk and animal feces of different livestock farms.BMC microbiology · 2025Article
- Exploring bovine brucellosis in Bangladesh: Current scenario and future outlook.Journal of advanced veterinary and animal research · 2024Review
- Serological prevalence ofOne health (Amsterdam, Netherlands) · 2024Article
- Epidemiology and laboratory testing of Brucella spondylitis.Scientific reports · 2024Article
- Clinical characterization of brucellosis in children from non-pastoral areas: a report of five cases.BMC infectious diseases · 2024Article
- Association Between Diagnostic Delays and Spinal Involvement in Human Brucellosis: A Retrospective Case-Control Study.Open forum infectious diseases · 2024Article
- Article
- Clinical characteristic, management, and outcomes of cervical spinal brucellosis: a retrospective cohort study over 1-year postoperative follow-up.Journal of orthopaedic surgery and research · 2024Article
- Molecular and serological diagnosis of multiple bacterial zoonoses in febrile outpatients in Garissa County, north-eastern Kenya.Scientific reports · 2024Article
- Brucellosis: Unveiling the complexities of a pervasive zoonotic disease and its global impacts.Open veterinary journal · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
backgroundBrucellosis has extensive clinical spectrum, clinicians have insufficient understanding of the disease, and the misdiagnosis rate is still high. By collecting and analyzing the clinical characteristics of patients with brucellosis in Heilongjiang Province to provide guidance and reference for clinicians to make timely diagnosis and treatment.
methodsThe demographic and epidemiological characteristics, clinical features, complications, laboratory findings were retrospectively evaluated in 850 brucellosis patients admitted in the Department of Infectious Diseases of the First Affiliated Hospital of Harbin Medical University and the Second Hospital of Daqing from 2012 to 2017.
resultsOf the 850 patients, the most common clinical manifestations were fever (93.3%), joint pain (69.8%), sweating (45.2%), fatigue (38.6%), and splenomegaly (34.0%). Peripheral arthritis, spondylitis and epididymal-orchitis were the common complications. Of the 398 patients who were followed up and completed treatment, 22 (5.5%) had relapse.
conclusionsBrucellosis is a multisystem disease with diverse clinical manifestations. In areas where brucellosis is endemic, the possibility of the disease should be considered in patients with unexplained fever and joints pain. In addition, the high rate of relapse is mainly due to the misdiagnosis of complications, so local CT or MRI examination is necessary for patients with joint pain and low back pain. Timely diagnosis, early detection of complications are essential to improve the prognosis and reduce relapse.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.