Evidence map›Paper›PMID 31109150›Full record

ReviewInternational journal of molecular sciences2019

Gap Junction Channels of Innexins and Connexins: Relations and Computational Perspectives.

Alejandro Sánchez, Carlos Castro, Dora-Luz Flores, Everardo Gutiérrez, Pierre Baldi

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Unnexin is a protein subunit of a large-pore channel expressed by unicellular organisms.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  6. Review
  7. Article
  8. Mutations of CX46/CX50 and Cataract Development.Frontiers in molecular biosciences · 2022
    Review
  9. Article
  10. Article
  11. Article
  12. Glial Chloride Channels in the Function of the Nervous System Across Species.Advances in experimental medicine and biology · 2021
    Article
  13. Article
  14. Review
  15. Review
  16. Review
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Alejandro SánchezFacultad de Ciencias, Universidad Autónoma de Baja California, Ensenada, Baja California 22860, Mexico. alejandrosg@uabc.edu.mx.ORCID 0000-0002-1880-0036
Carlos CastroFacultad of Ingeniería, Arquitectura y Diseño, Universidad Autónoma de Baja California, Ensenada, Baja California 22860, Mexico. carlos.castro98@uabc.edu.mx.ORCID 0000-0002-1109-4239
Dora-Luz FloresFacultad of Ingeniería, Arquitectura y Diseño, Universidad Autónoma de Baja California, Ensenada, Baja California 22860, Mexico. dflores@uabc.edu.mx.ORCID 0000-0002-2623-3772
Everardo GutiérrezFacultad de Ciencias, Universidad Autónoma de Baja California, Ensenada, Baja California 22860, Mexico. everardo.gutierrez@uabc.edu.mx.ORCID 0000-0002-9297-7876
Pierre BaldiDepartment of Computer Science, Institute for Genomics and Bioinformatics, and Center for Machine Learning and Intelligent Systems, University of California, Irvine, CA 92697, USA. pfbaldi@uci.edu.
Universidad Autónoma de Baja California · MXUniversity of California, Irvine · US

Funding

Comisión México-Estados Unidos para el Intercambio Educativo y Cultural PS00275077Consejo Nacional de Ciencia y Tecnología 175415Consejo Nacional de Ciencia y Tecnología 763840
6 · The paper itself

Abstract

Gap junction (GJ) channels in invertebrates have been used to understand cell-to-cell communication in vertebrates. GJs are a common form of intercellular communication channels which connect the cytoplasm of adjacent cells. Dysregulation and structural alteration of the gap junction-mediated communication have been proven to be associated with a myriad of symptoms and tissue-specific pathologies. Animal models relying on the invertebrate nervous system have exposed a relationship between GJs and the formation of electrical synapses during embryogenesis and adulthood. The modulation of GJs as a therapeutic and clinical tool may eventually provide an alternative for treating tissue formation-related diseases and cell propagation. This review concerns the similarities between

Indexed as

AnimalsComputer SimulationConnexinsGap JunctionsHumansMachine LearningModels, BiologicalNervous SystemProtein ConformationConnexinscentral nervous systemconnexingap junctionsinnexinleechmachine learning

Identifiers

PMID31109150
PMCPMC6566657
OpenAlexW2945444536

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.