ReviewInternational journal of molecular sciences2019
Mechanistic Insights into the Antimicrobial Actions of Metallic Nanoparticles and Their Implications for Multidrug Resistance.
Review in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 169 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
169 citing papers in PubMed, 1 synthesis or guideline pooled it, 483 citations in OpenAlex.
- Metal Nanoparticles in Infection and Immunity.Immunological investigations · 2020Pooled it
- Effective bio-activities of the metal nanoparticles mycosynthesized by the plants' fungal endophytes.Microbial cell factories · 2026Review
- Antimicrobial synergism of silver and zinc oxide nanoparticles with antibiotics against clinical isolate of Cutibacterium acnes.International microbiology : the official journal of the Spanish Society for Microbiology · 2026Article
- Review
- Metal nanoparticles as next-generation therapeutics against antimicrobial resistance: mechanisms, functionalization, and translational potential.Molecular biology reports · 2026Review
- Topical strategies for antimicrobial delivery of peptide medicines for the management of chronic wounds.Discover nano · 2026Review
- Silver-Doped Mesoporous Calcium Phosphate for Controlled Amoxicillin Delivery and Modulation of Osteoblast-like Cell Response.Pharmaceutics · 2026Article
- Citrate reduced gold nanoparticles lowered lipid content in differentiated 3T3-L1 adipocytes by altering the expression of adipogenic genes.Discover nano · 2026Article
- Calcium Phosphate Nanostructured Biocomposites with Applications in Bone Tissue Engineering.Materials (Basel, Switzerland) · 2026Review
- Oxidation Mechanism in Bigels and Emulgels-Challenges and Solutions.Molecules (Basel, Switzerland) · 2026Review
- Article
- Eco-friendly fabrication of silver nanoparticles fromRSC advances · 2026Article
- Magnetic Field-Driven Strategies for Biofilm Disruption: From Iron Oxide Nanoparticles to Adaptive Swarms of Magnetic Microrobots.ACS nano · 2026Review
- Emerging strategies of bacterial adaptation mechanisms to silver and metal oxide nanomaterials.FEMS microbiology reviews · 2026Review
- Biogenic gold nanoparticles conjugated with rhizobacteria enhance tomato growth and suppress pathogen infection.Frontiers in microbiology · 2026Article
- Metallic nanoparticles in the treatment of staphylococcus infections: a scoping review.BMC pharmacology & toxicology · 2025Article
- Biosynthesized Silver Selenide Nanoparticles fromMicroorganisms · 2025Article
- Vitamin-Conjugated Metallic Nanoparticles: Applications for Antimicrobial and Anti-Cancer Drug Delivery.Molecules (Basel, Switzerland) · 2025Review
- Antibacterial, anti-biofilm and anti-virulence activity of biosynthesized silver nanoparticles against drug-resistant Staphylococcus aureus.Veterinary research communications · 2025Article
- Bacterial cellulose doped with ZnO as a multifunctional bioactive platform for curcumin and propolis immobilization: synthesis, characterization, and wound healing potential.Microbial cell factories · 2025Article
109 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 3 institutions in 3 countries.
Funding
Abstract
Multiple drug-resistant bacteria are a severe and growing public health concern. Because relatively few antibiotics have been approved over recent years and because of the inability of existing antibiotics to combat bacterial infections fully, demand for unconventional biocides is intense. Metallic nanoparticles (NPs) offer a novel potential means of fighting bacteria. Although metallic NPs exert their effects through membrane protein damage, superoxide radicals and the generation of ions that interfere with the cell granules leading to the formation of condensed particles, their antimicrobial potential, and mechanisms of action are still debated. This article discusses the action of metallic NPs as antibacterial agents, their mechanism of action, and their effect on bacterial drug resistance. Based on encouraging data about the antibacterial effects of NP/antibiotic combinations, we propose that this concept be thoroughly researched to identify means of combating drug-resistant bacteria.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.