Evidence map›Paper›PMID 31108968›Full record

ArticleInternational journal of molecular sciences2019

Melatonin MT

Martha López-Canul, Seung Hyun Min, Luca Posa, Danilo De Gregorio, Annalida Bedini, Gilberto Spadoni, Gabriella Gobbi, Stefano Comai

Open access · goldAbstract readComparative Study
In one paragraph

Article in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 27 citations in OpenAlex.

  1. Structural and Dynamics Insights into Melatonin Binding to MT1 Receptor.Chembiochem : a European journal of chemical biology · 2026
    Article
  2. Circadian Rhythms of Body Temperature and Locomotor Activity in Spontaneously Hypertensive Rats under Frequent Changes in Light Conditions.Pathophysiology : the official journal of the International Society for Pathophysiology · 2024
    Article
  3. Article
  4. Article
  5. Article
  6. MT1 and MT2 melatonin receptors play opposite roles in brain cancer progression.Journal of molecular medicine (Berlin, Germany) · 2021
    Article
  7. Article
  8. Sleep and thermoregulation.Current opinion in physiology · 2020
    Review
  9. Review
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Martha López-CanulNeurobiological Psychiatry Unit, Department of Psychiatry, McGill University Health Center (MUHC), McGill University, Montreal, QC H3A1A1, Canada. martha.lopezcanul@mcgill.ca.
Seung Hyun MinNeurobiological Psychiatry Unit, Department of Psychiatry, McGill University Health Center (MUHC), McGill University, Montreal, QC H3A1A1, Canada. seung.min@mail.mcgill.ca.
Luca PosaNeurobiological Psychiatry Unit, Department of Psychiatry, McGill University Health Center (MUHC), McGill University, Montreal, QC H3A1A1, Canada. luca.posa@mail.mcgill.ca.ORCID 0000-0002-6464-1961
Danilo De GregorioNeurobiological Psychiatry Unit, Department of Psychiatry, McGill University Health Center (MUHC), McGill University, Montreal, QC H3A1A1, Canada. danilo.degregorio@mail.mcgill.ca.
Annalida BediniDepartment of Biomolecular Sciences, University Carlo Bo, 61029 Urbino, Italy. annalida.bedini@uniurb.it.
Gilberto SpadoniDepartment of Biomolecular Sciences, University Carlo Bo, 61029 Urbino, Italy. gilberto.spadoni@uniurb.it.
Gabriella GobbiNeurobiological Psychiatry Unit, Department of Psychiatry, McGill University Health Center (MUHC), McGill University, Montreal, QC H3A1A1, Canada. gabriella.gobbi@mcgill.ca.
Stefano ComaiNeurobiological Psychiatry Unit, Department of Psychiatry, McGill University Health Center (MUHC), McGill University, Montreal, QC H3A1A1, Canada. comai.stefano@hsr.it.ORCID 0000-0002-5686-7194
McGill University Health Centre · CAUniversity of Urbino · ITVita-Salute San Raffaele University · IT

Funding

Canadian Institutes of Health Research MOP-130285Ministère de l'Économie, de la Science et de l'Innovation - Québec PSR-SIIRI
6 · The paper itself

Abstract

Melatonin (MLT) is a neurohormone that regulates many physiological functions including sleep, pain, thermoregulation, and circadian rhythms. MLT acts mainly through two G-protein-coupled receptors named MT

Indexed as

AcetamidesAniline CompoundsAnimalsBody TemperatureInjections, SubcutaneousMaleMelatoninPhotoperiodRatsRats, WistarReceptor, Melatonin, MT1Receptor, Melatonin, MT2TetrahydronaphthalenesTryptamines4-phenyl-2-propionamidotetralineAcetamidesAniline CompoundsluzindoleMelatoninN-(2-((3-bromophenyl)-(4-fluorophenyl)amino)ethyl)acetamideReceptor, Melatonin, MT1Receptor, Melatonin, MT2TetrahydronaphthalenesTryptaminesbody temperaturelight/dark cyclemelatoninMT1 receptorsMT2 receptorsMT3 receptors

Identifiers

PMID31108968
PMCPMC6566544
OpenAlexW2946513065

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.