Evidence map›Paper›PMID 31108918›Full record

ArticleBiomolecules2019

Relative Telomere Length and Cardiovascular Risk Factors.

Moritz Koriath, Christian Müller, Norbert Pfeiffer, Stefan Nickels, Manfred Beutel, Irene Schmidtmann, Steffen Rapp, Thomas Münzel, Dirk Westermann, Mahir Karakas and 4 more

Open access · goldAbstract read
In one paragraph

Article in Biomolecules, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Telomere Length: A Cardiovascular Biomarker and a Novel Therapeutic Target.International journal of molecular sciences · 2022
    Review
  8. Article
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 1 country.

Moritz KoriathClinic of General and Interventional Cardiology, University Heart Center Hamburg-Eppendorf, 20246 Hamburg, Germany. m.koriath@uke.de.ORCID 0000-0002-4542-542X
Christian MüllerClinic of General and Interventional Cardiology, University Heart Center Hamburg-Eppendorf, 20246 Hamburg, Germany. Christian_m@gmx.net.
Norbert PfeifferDepartment of Ophthalmology, University Medical Center of the Johannes Gutenberg-University Mainz, 55131 Mainz, Germany. norbert.pfeiffer@unimedizin-mainz.de.
Stefan NickelsDepartment of Ophthalmology, University Medical Center of the Johannes Gutenberg-University Mainz, 55131 Mainz, Germany. Stefan.Nickels@unimedizin-mainz.de.ORCID 0000-0003-0415-2354
Manfred BeutelDepartment of Psychosomatic Medicine and Psychotherapy, University Medical Center of the Johannes Gutenberg-University Mainz, 55131 Mainz, Germany. Manfred.Beutel@unimedizin-mainz.de.
Irene SchmidtmannInstitute for Medical Biostatistics, Epidemiology and Informatics, Johannes Gutenberg-University Mainz, 55131 Mainz, Germany. irene.schmidtmann@unimedizin-mainz.de.
Steffen RappInstitute for Molecular Genetics, Johannes Gutenberg University, 55131 Mainz, Germany. Steffen.Rapp@unimedizin-mainz.de.
Thomas MünzelDZHK (German Center for Cardiovascular Research), Partner Site Rhine-Main, 55131 Mainz, Germany. tmuenzel@uni-mainz.de.ORCID 0000-0001-5503-4150
Dirk WestermannClinic of General and Interventional Cardiology, University Heart Center Hamburg-Eppendorf, 20246 Hamburg, Germany. d.westermann@uke.de.
Mahir KarakasClinic of General and Interventional Cardiology, University Heart Center Hamburg-Eppendorf, 20246 Hamburg, Germany. m.karakas@uke.de.
Philipp S WildDZHK (German Center for Cardiovascular Research), Partner Site Rhine-Main, 55131 Mainz, Germany. philipp.wild@unimedizin-mainz.de.
Karl J LacknerDZHK (German Center for Cardiovascular Research), Partner Site Rhine-Main, 55131 Mainz, Germany. karl.lackner@unimedizin-mainz.de.
Stefan BlankenbergClinic of General and Interventional Cardiology, University Heart Center Hamburg-Eppendorf, 20246 Hamburg, Germany. s.blankenberg@uke.de.
Tanja ZellerClinic of General and Interventional Cardiology, University Heart Center Hamburg-Eppendorf, 20246 Hamburg, Germany. t.zeller@uke.de.
Johannes Gutenberg University Mainz · DEUniversität Hamburg · DE

Funding

European Research Area Network (ERA-Net) PREMED-CADGerman Center for Cardiovascular Research (DZHK) 81Z1710101Stiftung Rheinland-Pfalz für Innovation AZ 961 - 386261/733
6 · The paper itself

Abstract

(1) Background: Telomeres are repetitive DNA sequences located at the extremities of chromosomes that maintain genetic stability. Telomere biology is relevant to several human disorders and diseases, specifically cardiovascular disease. To better understand the link between cardiovascular disease and telomere length, we studied the effect of relative telomere length (RTL) on cardiovascular risk factors in a large population-based sample. (2) Methods: RTL was measured by a real-time quantitative polymerase chain reaction in subjects of the population-based Gutenberg Health Study (

Indexed as

Telomere HomeostasisAgedAge FactorsBody Mass IndexCardiovascular DiseasesCholesterolFemaleHumansMaleMiddle AgedSmokingTriglyceridesCholesterolTriglyceridesageingcardiovascular diseasecardiovascular risk factorstelomere lengthtelomeres

Identifiers

PMID31108918
PMCPMC6572569
OpenAlexW2945930034

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.