Evidence map›Paper›PMID 31108895›Full record

ReviewMolecules (Basel, Switzerland)2019

Determination of Kanamycin by High Performance Liquid Chromatography.

Xingping Zhang, Jiujun Wang, Qinghua Wu, Li Li, Yun Wang, Hualin Yang

Open access · goldAbstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
5.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 134 citations in OpenAlex.

  1. Strand displacement-triggered biocatalytic precipitation on ZIF-8/BiAnalytical and bioanalytical chemistry · 2026
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  4. Review
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  8. Reactivation of hidden-latentAntimicrobial agents and chemotherapy · 2025
    Article
  9. Article
  10. Chemiluminescence detection of kanamycin by DNA aptamer regulating peroxidase-like activity of CoAnalytical sciences : the international journal of the Japan Society for Analytical Chemistry · 2025
    Article
  11. Review
  12. Review
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  15. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Xingping ZhangCollege of Life Science, Yangtze University, Jingzhou 434025, China. xpzhang1987@163.com.
Jiujun WangCollege of Life Science, Yangtze University, Jingzhou 434025, China. wangjiujun2018@126.com.
Qinghua WuCollege of Life Science, Yangtze University, Jingzhou 434025, China. wqh212@hotmail.com.
Li LiCollege of Life Science, Yangtze University, Jingzhou 434025, China. lily2012@yangtzeu.edu.cn.
Yun WangCollege of Life Science, Yangtze University, Jingzhou 434025, China. 1wangyun@yangtzeu.edu.cn.
Hualin YangCollege of Life Science, Yangtze University, Jingzhou 434025, China. yanghualin2005@126.com.
Yangtze University · CN

Funding

National Natural Science Foundation of China 31601536
6 · The paper itself

Abstract

Kanamycin is an aminoglycoside antibiotic widely used in treating animal diseases caused by Gram-negative and Gram-positive infections. Kanamycin has a relatively narrow therapeutic index, and can accumulate in the human body through the food chain. The abuse of kanamycin can have serious side-effects. Therefore, it was necessary to develop a sensitive and selective analysis method to detect kanamycin residue in food to ensure public health. There are many analytical methods to determine kanamycin concentration, among which high performance liquid chromatography (HPLC) is a common and practical tool. This paper presents a review of the application of HPLC analysis of kanamycin in different sample matrices. The different detectors coupled with HPLC, including Ultraviolet (UV)/Fluorescence, Evaporative Light Scattering Detector (ELSD)/Pulsed Electrochemical Detection (PED), and Mass Spectrometry, are discussed. Meanwhile, the strengths and weaknesses of each method are compared. The pre-treatment methods of food samples, including protein precipitation, liquid-liquid extraction (LLE), and solid-phase extraction (SPE) are also summarized in this paper.

Indexed as

AnimalsAnti-Bacterial AgentsChemical FractionationChromatography, High Pressure LiquidFood AnalysisFood ChainHumansKanamycinAnti-Bacterial AgentsKanamycindifferent detectorsfood contaminationHPLCKanamycinsample pre-treatment

Identifiers

PMID31108895
PMCPMC6572613
OpenAlexW2945441911

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.