Evidence map›Paper›PMID 31108847›Full record

ArticleInternational journal of molecular sciences2019

Pharmacological Targeting of the ER-Resident Chaperones GRP94 or Cyclophilin B Induces Secretion of IL-22 Binding Protein Isoform-1 (IL-22BPi1).

Paloma Gómez-Fernández, Andoni Urtasun, Ianire Astobiza, Jorge Mena, Iraide Alloza, Koen Vandenbroeck

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Paloma Gómez-FernándezNeurogenomiks Group, Department of Neuroscience, University of the Basque Country (UPV/EHU), 48490 Leioa, Spain. paloma.gomez.fernandez@gmail.com.ORCID 0000-0002-2086-0652
Andoni UrtasunNeurogenomiks Group, Department of Neuroscience, University of the Basque Country (UPV/EHU), 48490 Leioa, Spain. a.urtasun.arricaberri@gmail.com.
Ianire AstobizaNeurogenomiks Group, Department of Neuroscience, University of the Basque Country (UPV/EHU), 48490 Leioa, Spain. nireaspe@hotmail.com.
Jorge MenaNeurogenomiks Group, Department of Neuroscience, University of the Basque Country (UPV/EHU), 48490 Leioa, Spain. jorgemena65@outlook.com.
Iraide AllozaNeurogenomiks Group, Department of Neuroscience, University of the Basque Country (UPV/EHU), 48490 Leioa, Spain. iraide.alloza@ehu.eus.
Koen VandenbroeckNeurogenomiks Group, Department of Neuroscience, University of the Basque Country (UPV/EHU), 48490 Leioa, Spain. k.vandenbroeck@ikerbasque.org.ORCID 0000-0002-6967-6485
University of the Basque Country · ESIkerbasque · ES

Funding

Ministerio de Economía y Competitividad SAF2016-74891ROsasun Saila, Eusko Jaurlaritzako IT512-10, PPG17/44
6 · The paper itself

Abstract

Of the three interleukin-22 binding protein (IL-22BP) isoforms produced by the human

Indexed as

BenzoquinonesBinding SitesCyclophilinsCyclosporineEndoplasmic ReticulumEndoplasmic Reticulum Chaperone BiPGene Expression ProfilingGlycosylationHEK293 CellsHumansLactams, MacrocyclicMembrane GlycoproteinsMonocytesProtein BindingProtein IsoformsProteolysisBenzoquinonescyclophilin BCyclophilinsCyclosporineEndoplasmic Reticulum Chaperone BiPendoplasmingeldanamycinHSPA5 protein, humanIL22RA2 protein, humanLactams, MacrocyclicMembrane GlycoproteinsProtein IsoformsReceptors, InterleukinBiPcyclophilincyclosporin AERgeldanamycingp96GRP78GRP94IL-22BPIL22RA2isoformUPR

Identifiers

PMID31108847
PMCPMC6566634
OpenAlexW2945357090

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.