Evidence map›Paper›PMID 31108214›Full record

ArticleNeuroImage2019

The influence of brain iron on myelin water imaging.

Christoph Birkl, Anna Maria Birkl-Toeglhofer, Verena Endmayr, Romana Höftberger, Gregor Kasprian, Claudia Krebs, Johannes Haybaeck, Alexander Rauscher

Open access · greenAbstract read
In one paragraph

Article in NeuroImage, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed
8.0field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 89 citations in OpenAlex.

  1. Trial
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  4. Review
  5. Article
  6. Reduced myelin contributes to cognitive impairment in patients with monogenic small vessel disease.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025
    Article
  7. Article
  8. Observational
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Improved myelin water imaging using BImaging neuroscience (Cambridge, Mass.) · 2024
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 3 countries.

Christoph BirklUBC MRI Research Centre, University of British Columbia, Vancouver, BC, Canada; Department of Neurology, Medical University of Graz, Austria. Electronic address: christoph.birkl@ubc.ca.
Anna Maria Birkl-ToeglhoferDepartment of Pathology, Neuropathology and Molecular Pathology, Medical University of Innsbruck, Austria; Diagnostic and Research Institute of Pathology, Medical University of Graz, Austria.
Verena EndmayrInstitute of Neurology, Medical University of Vienna, Austria.
Romana HöftbergerInstitute of Neurology, Medical University of Vienna, Austria.
Gregor KasprianDepartment of Biomedical Imaging and Image-Guided Therapy, Medical University of Vienna, Austria.
Claudia KrebsDepartment of Cellular & Physiological Sciences, University of British Columbia, Vancouver, BC, Canada.
Johannes HaybaeckDepartment of Pathology, Neuropathology and Molecular Pathology, Medical University of Innsbruck, Austria; Diagnostic and Research Institute of Pathology, Medical University of Graz, Austria; Department of Pathology, Medical Faculty, Otto-von-Guerecke University Magdeburg, Germany.
Alexander RauscherUBC MRI Research Centre, University of British Columbia, Vancouver, BC, Canada; Department of Physics & Astronomy, University of British Columbia, Vancouver, BC, Canada; Department of Pediatrics (Division of Neurology), University of British Columbia, Vancouver, BC, Canada.
Medical University of Vienna · ATUniversity of British Columbia Hospital · CAInnsbruck Medical University · ATMedical University of Graz · ATUniversity of British Columbia · CA

Funding

Austrian Science Fund FWF J 4038
6 · The paper itself

Abstract

With myelin playing a vital role in normal brain integrity and function and thus in various neurological disorders, myelin sensitive magnetic resonance imaging (MRI) techniques are of great importance. In particular, multi-exponential T

Indexed as

IronMyelin SheathAgedAged, 80 and overAutopsyBody WaterFemaleHumansMagnetic Resonance ImagingMaleMiddle AgedNeuroimagingWhite MatterIronBrainIronMyelinMyelin water imagingQuantitative MRIWhite matter

Identifiers

PMID31108214
PMCPMC7610792
OpenAlexW2944868864

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.