ArticleMedical physics2019
A depth encoding PET detector using four-crystals-to-one-SiPM coupling and light-sharing window method.
Article in Medical physics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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3 citing papers in PubMed, 23 citations in OpenAlex.
- Potential and challenges of Positron Emission Tomography beyond conventional preclinical and clinical imaging.Zeitschrift fur medizinische Physik · 2026Review
- Pathophysiology characterization of Alzheimer's disease in South China's aging population: for the Greater-Bay-Area Healthy Aging Brain Study (GHABS).Alzheimer's research & therapy · 2024Article
- A Novel Portable Gamma Radiation Sensor Based on a Monolithic Lutetium-Yttrium Oxyorthosilicate Ring.Sensors (Basel, Switzerland) · 2021Article
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7 authors at 3 institutions in 2 countries.
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Abstract
purposeDepth of interaction (DOI) decoding capability is of great importance for positron emission tomography (PET) requiring high resolution. In this study, we presented a novel low-cost DOI detector design with four crystals coupling to one SiPM, based on the method of rectangular light-sharing window (RLSW). A prototype detector was constructed, calibrated, and assessed using the methods of homogeneous radiation and flood map analysis.
methodsThe DOI detector was constructed with a 4 × 4 array of lutetium-yttrium oxyorthosilicate (LYSO) crystals (2.95 mm × 2.95 mm × 20 mm
resultsAll 16 crystals are distinctly separated from each other in the flood map. Twelve crystals, including four central crystals and eight edge crystals, have the DOI capability. The full width half maximum (FWHM) of the DOI measurements of the central crystals and the edge crystals are 3.06 ± 0.08 and 3.79 ± 0.15 mm, respectively, for the configuration with four crystals coupling to one SiPM. By contrast, the FWHMs (3.98 ± 0.16 and 5.12 ± 0.38 mm, respectively) are slightly worse for the configuration with one crystal coupling to one SiPM. The average and standard deviation (STD) of the FWHM energy resolutions of the DOI detector and non-DOI detector were 10.2% ± 0.7% and 10.7% ± 1.7%, respectively. Their FWHM coincidence timing resolutions were 197.0 ± 9.6 and 206.4 ± 13.3 ps, respectively. The RLSW had no significant impact on the energy resolutions and timing resolutions of the DOI detector.
conclusionsThe novel four-crystals-to-one-SiPM coupling technology is a cost-efficient approach to construct high-performance detector modules with DOI capability. The methods of homogeneous radiation and flood map analysis are easy to perform and of good performance. Those methods can be adapted in the clinic PET scanners to enable the capability of DOI measurements.
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