Evidence map›Paper›PMID 31107967›Full record

ArticleHepatology (Baltimore, Md.)2019

Quality Measures, All-Cause Mortality, and Health Care Use in a National Cohort of Veterans With Cirrhosis.

Marina Serper, David E Kaplan, Justine Shults, Peter P Reese, Lauren A Beste, Tamar H Taddei, Rachel M Werner

Open access · greenAbstract read
In one paragraph

Article in Hepatology (Baltimore, Md.), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 48 citations in OpenAlex.

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  8. Associations of Race and Ethnicity with Hepatocellular Carcinoma, Decompensation, and Mortality in US Veterans with Cirrhosis.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2023
    Article
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  13. The Future of Quality Improvement for Cirrhosis.Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society · 2021
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Marina SerperCorporal Michael J. Crescenz VA Medical Center, Philadelphia, PA.ORCID 0000-0003-4899-2160
David E KaplanCorporal Michael J. Crescenz VA Medical Center, Philadelphia, PA.
Justine ShultsDepartment of Biostatistics, Epidemiology and Informatics, University of Pennsylvania, Philadelphia, PA.
Peter P ReeseLeonard Davis Institute of Health Economics, Philadelphia, PA.
Lauren A BesteHealth Services Research and Development, Seattle, WA.
Tamar H TaddeiVA Connecticut Healthcare System, West Haven, CT.
Rachel M WernerCorporal Michael J. Crescenz VA Medical Center, Philadelphia, PA.
Philadelphia VA Medical Center · USUniversity of Pennsylvania · USUniversity of Washington · USYale University · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Midcareer Mentoring Award for Patient-Oriented Research in AgingK24AG047908 · NIA · UNIVERSITY OF PENNSYLVANIA · PI WERNER, RACHEL M · 2014 to 2024
$2.0M
Developing technology-based approaches to improve access and quality of care in cirrhosisK23DK115897 · NIDDK · UNIVERSITY OF PENNSYLVANIA · PI SERPER, MARINA · 2018 to 2022
$961k
Training in Healthcare Financing, Organization and Delivery for Aging PopulationsT32AG051090 · NIA · UNIVERSITY OF PENNSYLVANIA · PI PAULY, MARK, WERNER, RACHEL M · 2015 to 2019
$652k
NCATS NIH HHS UL1 TR001863NIA NIH HHS K24 AG047908NIA NIH HHS T32 AG051090NIDDK NIH HHS K23 DK115897
6 · The paper itself

Abstract

Decompensated cirrhosis is associated with high morbidity and mortality. However, no standardized quality measures (QMs) have yet been adopted widely. The Veterans Affairs (VA) Advanced Liver Disease Technical Advisory Group recently developed a set of six internal QMs to guide quality improvement efforts in cirrhosis in the domains of access to care, hepatocellular carcinoma surveillance, variceal surveillance, quality of inpatient care for upper gastrointestinal bleeding, and cirrhosis-related rehospitalizations. We aimed to (1) quantify adherence to cirrhosis QMs and (2) determine whether adherence was associated with all-cause mortality and health care use within a large national cohort of veterans with cirrhosis. We performed a retrospective study using data from the Veterans Outcomes and Costs Asociated with Liver Disease cohort of 121,129 patients newly diagnosed with cirrhosis from January 1, 2008, to December 31, 2016, at 128 VA facilities. The mean follow-up time was 2.7 years (interquartile range, 1.1-5.1 years). Adherence to outpatient access to specialty care was 71%, variceal surveillance was 32%, and early postdischarge care was 54%. In adjusted analyses, outpatient access to specialty care (hazard ratio [HR], 0.80; 95% confidence interval [CI], 0.78-0.82), hepatocellular carcinoma surveillance (HR, 0.92; 95% CI, 0.90-0.95), variceal surveillance (HR, 0.93; 95% CI, 0.89-0.99), and early postdischarge care (HR, 0.57; 95% CI, 0.54-0.60) were associated with lower all-cause mortality. Readmissions after 30 days (HR, 1.53; 1.46-1.60) and 90 days (HR, 1.88; 95% CI, 1.54-1.70) were associated with higher all-cause mortality. Higher adherence to QMs was also associated with lower inpatient health care use. Conclusion: Five of the six proposed VA cirrhosis QMs were measurable using existing data sources, associated with mortality and health care use, and may be used to guide future quality improvement efforts in cirrhosis.

Indexed as

Quality of Health CareAgedFemaleHealth ServicesHumansLiver CirrhosisMaleMiddle AgedQuality ImprovementRetrospective StudiesVeterans

Identifiers

PMID31107967
PMCPMC6864236
OpenAlexW2944864464

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.