Evidence map›Paper›PMID 31107507›Full record

ArticleAmerican journal of epidemiology2019

Early-Life Growth and Benign Breast Disease.

Mandy Goldberg, Barbara A Cohn, Lauren C Houghton, Julie D Flom, Ying Wei, Piera Cirillo, Karin B Michels, Mary Beth Terry

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in American journal of epidemiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Mandy GoldbergDepartment of Epidemiology, Mailman School of Public Health, Columbia University, New York, New York.
Barbara A CohnChild Health and Development Studies, Public Health Institute, Berkeley, California.
Lauren C HoughtonDepartment of Epidemiology, Mailman School of Public Health, Columbia University, New York, New York.
Julie D FlomDepartment of Epidemiology, Mailman School of Public Health, Columbia University, New York, New York.
Ying WeiDepartment of Biostatistics, Mailman School of Public Health, Columbia University, New York, New York.
Piera CirilloChild Health and Development Studies, Public Health Institute, Berkeley, California.
Karin B MichelsDepartment of Epidemiology, Fielding School of Public Health, University of California, Los Angeles, Los Angeles, California.
Mary Beth TerryDepartment of Epidemiology, Mailman School of Public Health, Columbia University, New York, New York.
Columbia University · USPublic Health Institute · USColumbia University Irving Medical Center · USUniversity of Freiburg · DE

Funding

True Metal fac coreP30ES009089 · NIEHS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI MATTHEW S PERZANOWSKI · 1998 to 2026
$44.7M
CANCER EPIDEMIOLOGY/BIOSTATISTICS/ENVIRONMENTAL SCIENCEST32CA009529 · NCI · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI NEUGUT, ALFRED I. · 1985 to 2012
$4.3M
Early Determinants of Mammographic DensityR01CA104842 · NCI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI TERRY, MARY BETH · 2004 to 2009
$2.6M
Early Determinants of Adult HealthP01AG023028 · NIA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI SUSSER, EZRA S. · 2003 to 2007
$2.5M
Early Determinants of Breast Cancer RiskK07CA090685 · NCI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI TERRY, MARY BETH · 2001 to 2006
$671k
NCI NIH HHS K07 CA090685NCI NIH HHS R01 CA104842NCI NIH HHS T32 CA009529NIA NIH HHS P01 AG023028NIEHS NIH HHS P30 ES009089
6 · The paper itself

Abstract

Using prospective data from the Early Determinants of Mammographic Density study (United States, 1959-2008, n = 1121), we examined the associations between maternal body size, birth size, and infant and early childhood growth during 3 time periods (0-4 months, 4-12 months, and 1-4 years) and benign breast disease (BBD) using multivariable logistic regression with generalized estimating equations. A total of 197 women (17.6%) reported receiving a diagnosis of BBD by a physician. Higher body mass index at age 7 years was inversely associated with BBD risk. Rapid weight gain from age 1 year to 4 years, defined as an increase of least 2 major percentiles (e.g., 5th, 10th, 25th, 50th, 75th, and 95th) relative to stable growth, defined as remaining within 2 percentiles, was also inversely associated with BBD (odds ratio (OR) = 0.51, 95% confidence interval (CI): 0.23, 1.15). In contrast, rapid weight gain in infancy was positively associated with BBD relative to stable growth (from 0 to 4 months, OR = 1.65, 95% CI: 1.04, 2.62; from 4 to 12 months, 1.85, 95% CI: 0.89, 3.85), independent of birth weight, which was not associated with BBD. Our results suggest that patterns of early-life weight gain are important to BBD risk. Thus, susceptibility to BBD, like susceptibility to breast cancer, might start in early life.

Indexed as

Body Mass IndexBreast DiseasesGrowthWeight GainAdultBirth WeightBody SizeChild, PreschoolFemaleHumansInfantMothersProspective StudiesYoung Adultbenign breast diseasebirth weightBMIbody sizeinfant growthmaternal size

Identifiers

PMID31107507
PMCPMC6736448
OpenAlexW2945175439

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.