ArticleJournal of clinical hypertension (Greenwich, Conn.)2019
Poor management of hypertension is an important precipitating factor for the development of acute aortic dissection.
Article in Journal of clinical hypertension (Greenwich, Conn.), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 27 citations in OpenAlex.
- Association between ambient temperature and acute type A aortic dissection in a Korean population: a 12-year dual-scale Poisson regression analysis.Journal of thoracic disease · 2026Article
- A Diagnostic Pitfall in the Emergency Department -Aortic Dissection Masquerading as Acute Paraplegia: A Case Report.Clinical practice and cases in emergency medicine · 2026Article
- Predictive value of preoperative neutrophil-to-lymphocyte ratio for prognosis in aortic dissection patients without hypertension following TEVAR.Frontiers in aging · 2026Article
- Successful multidisciplinary treatment of cardiac tamponade from type A aortic dissection rupture in a pregnant woman with pre-eclampsia: a case report.Journal of medical case reports · 2025Article
- Migraine and spontaneous coronary artery dissection: A retrospective case-control study.Headache · 2025Article
- Hypertension-Induced Biomechanical Modifications in the Aortic Wall and Their Role in Stanford Type B Aortic Dissection.Biomedicines · 2024Article
- Total aortic arch debranching with antegrade Thoracic Endovascular Aortic Repair (TEVAR) in acute non-A non-B aortic dissection.Journal of cardiothoracic surgery · 2024Article
- Ethanol Enhances Endothelial Rigidity by Targeting VE-Cadherin-Implications for Acute Aortic Dissection.Journal of clinical medicine · 2023Article
- An Evidenced-Based Review of Emergency Target Blood Pressure Management for Acute Aortic Dissection.Emergency medicine international · 2023Review
- Changes in the gut microbiome of patients with type a aortic dissection.Frontiers in microbiology · 2023Article
- Short-term effects of air pollution and weather changes on the occurrence of acute aortic dissection in a cold region.Frontiers in public health · 2023Article
- Risk Factors for Aortic Dissection.US cardiology · 2023Review
- MiR-15a-5p accelerated vascular smooth muscle cells viabilities and migratory abilities via targeting Bcl-2.Physiological research · 2022Article
- Hydrogen sulfide: A new therapeutic target in vascular diseases.Frontiers in endocrinology · 2022Review
- Single Cell RNA Sequencing Reveals the Pathogenesis of Aortic Dissection Caused by Hypertension and Marfan Syndrome.Frontiers in cell and developmental biology · 2022Article
- Gender Difference is Associated with Short-Term Outcomes in Non-Surgically Managed Acute Aortic Dissection Patients with Hypertension: A Retrospective Cohort Study.Risk management and healthcare policy · 2021Article
- Association of renal cyst and type A acute aortic dissection with hypertension.Journal of thoracic disease · 2020Article
- Impact of hypertension on short- and long-term survival of patients who underwent emergency surgery for type A acute aortic dissection.Journal of thoracic disease · 2020Article
- Poor management of hypertension is an important precipitating factor for the development of acute aortic dissection.Journal of clinical hypertension (Greenwich, Conn.) · 2019Article
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Hypertension is considered a key risk factor for acute aortic dissection (AAD). However, there is limited evidence demonstrating if hypertension management affects AAD development. The objective of this study was to investigate the role of hypertension management in AAD development in a Chinese population. A total of 825 AAD patients and 3300 age- and sex-matched controls were included. The authors analyzed data on demographics, chronic comorbidities, and hypertension management of all participants. Multiple logistic regression analysis was used to estimate the adjusted odds ratios (AOR) and 95% confidence intervals (95% CI) for the relationship between chronic comorbidities, as well as the management of hypertension and AAD risk. After adjusting for other related factors, multivariate logistic regression identified hypertension, chronic kidney disease, Marfan syndrome, history of cardiovascular surgery, and history of smoking as risk factors for AAD. Among the identified risk factors, hypertension was an important and controllable risk factor for AAD development. Thus, the authors further evaluated how hypertension management affects AAD development. A total of 848 controls and 585 AAD patients with hypertension were enrolled in this part of the study. Hypertensive patients with AAD had a longer history, higher stage, poorer medication compliance, and poor control rates of blood pressure, among which poor medication compliance (Irregular vs Regular P < 0.001; Never treated vs Regular P < 0.001) and uncontrolled hypertension (P < 0.001) significantly increased the risk of AAD development. In conclusion, uncontrolled hypertension and poor medication compliance are important precipitating and controllable factors for AAD development.
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