Evidence map›Paper›PMID 31106657›Full record

SynthesisRenal failure2019

Effects of exercise training on cardiovascular risk factors in kidney transplant recipients: a systematic review and meta-analysis.

Gang Chen, Liu Gao, Xuemei Li

Registry-linked trialOpen access · goldAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Renal failure, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06249477 (Weight Loss and Physical Activity Lifestyle Interventions In Post Liver And Kidney Transplants), which is not on this map. Cited by 20 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 4 pooled it
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06249477 nacompletednot on this mapstarted 2022, after this paper: background citation

Weight Loss and Physical Activity Lifestyle Interventions In Post Liver And Kidney Transplants

TypeinterventionalSponsorMassachusetts General HospitalRan2022 to 2023Enrolled24ConditionsWeight Loss, Lifestyle FactorsArmsWrist activity tracker and scale, Nutritional Coaching group sessions
3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 4 syntheses or guidelines pooled it, 38 citations in OpenAlex.

  1. Optimizing Quality of Life in Kidney Transplant Recipients Through Structured Exercise: A Systematic Review and Evidence-Based Guidelines.Medical science monitor : international medical journal of experimental and clinical research · 2024
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  10. SupervisedWorld journal of transplantation · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Gang Chena Department of Nephrology, Peking Union Medical College Hospital , Peking Union Medical College, Chinese Academy of Medical Science , Beijing , China.ORCID http://orcid.org/0000-0002-5314-4249
Liu Gaob Department of Endocrinology, The Third Hospital of Hebei Medical University , Key Orthopaedic Biomechanics Laboratory of Hebei Province , Shijiazhuang , China.ORCID https://orcid.org/0000-0002-9263-5614
Xuemei Lia Department of Nephrology, Peking Union Medical College Hospital , Peking Union Medical College, Chinese Academy of Medical Science , Beijing , China.
Chinese Academy of Medical Sciences & Peking Union Medical College · CNHebei Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWhether exercise can improve cardiovascular health in kidney transplant recipients (KTRs) is unclear. Therefore, we performed a systematic review of the effects of exercise on cardiovascular risk factors in this population setting.

methodsRandomized control trials (RCTs) evaluating the impact of exercise on major clinical outcomes in KTRs were identified by searches in Cochrane CENTRAL, PubMed, EMBASE, OVID and CBM updated to December 2018. The main outcomes of interest were blood pressure, lipid profile, blood glucose level, arterial stiffness, kidney function, body weight, body mass index, exercise tolerance (VO

resultsAfter screening 445 studies in the database, we included 12 RCTs in the review and 11 RCTs for further qualitative analysis. The results indicate a significant improvement in small arterial stiffness [mean difference (MD): -1.14, 95% confidence interval (CI): -2.19-0.08, p = .03], VO

conclusionExercise intervention in KTRs improves arterial stiffness but does not consistently contribute to the modification of other CVD risk factors like hypertension, dyslipidemia, hyperglycemia, decreased kidney function and obesity. Exercise also improves exercise tolerance and QOL in KTRs.

Indexed as

Transplant RecipientsCardiovascular DiseasesCardiovascular SystemExerciseExercise TherapyHumansKidney TransplantationQuality of LifeRandomized Controlled Trials as TopicRisk FactorsTreatment Outcomearterial stiffnesscardiovascular diseaseExercisekidney transplantmeta-analysis

Identifiers

PMID31106657
PMCPMC6534232
OpenAlexW2945337996

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.