ArticleAddiction (Abingdon, England)2019
Cannabis use as a risk factor for causing motor vehicle crashes: a prospective study.
Article in Addiction (Abingdon, England), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 2 of them syntheses that pooled it.
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Who cites it
34 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Road hazard: a systematic review of traffic injuries following recreational cannabis legalization.CJEM · 2024Pooled it
- Cannabis Use and Car Crashes: A Review.Frontiers in psychiatry · 2021Pooled it
- Pediatric Trauma Trends Before and After Recreational Cannabis Legalization in Nevada: A Retrospective Repeated Cross-Sectional Study.Children (Basel, Switzerland) · 2026Article
- Noncompliance with laws to prevent polysubstance misuse: Recreational cannabis sales to apparently alcohol-intoxicated customers.Alcohol, clinical & experimental research · 2026Article
- Per Se Driving Under the Influence of Cannabis Statutes and Blood Delta-9-Tetrahydrocannabinol Concentrations following Short-Term Cannabis Abstinence.Clinical chemistry · 2025Article
- An Open-Road Driving Performance Task to Examine Long-Term Medical Marijuana Use and Prescription Opioid Positivity Among Adults Aged 50 Years and Older: Protocol for an Observational Trial.JMIR research protocols · 2025Article
- Prevalence of Impairing Substance Use in Injured Drivers.JAMA network open · 2025Article
- Attitudes toward driving after cannabis use: a systematic review.Journal of cannabis research · 2024Review
- Implications of using administrative healthcare data to identify risk of motor vehicle crash-related injury: the importance of distinguishing crash from crash-related injury.Injury epidemiology · 2024Article
- Heavy Lifetime Cannabis Use and Mortality by Sex.JAMA network open · 2024Article
- Cannabis and Alcohol Involvement in Motor Vehicle Crashes: Reflections in the Era of Legalization.American journal of public health · 2024Article
- Observational
- Drug driving: a secondary analysis of factors associated with driving under the influence of cannabis in Jamaica.BMJ open · 2024Article
- Why are the police against drug policy liberalisation?Nordisk alkohol- & narkotikatidskrift : NAT · 2023Article
- In vitro evaluation of cell viability and expression profile of growth factors in mouse Sertoli cells exposed to Delta-9-tetrahydrocannabinol: a mechanistic insight into the cannabinoid-induced testicular toxicity.BMC pharmacology & toxicology · 2023Article
- Risk of Motor Vehicle Collisions and Culpability among Older Drivers Using Cannabis: A Meta-Analysis.Brain sciences · 2023Review
- The Effects of β-myrcene on Simulated Driving and Divided Attention: A Double-Blind, Placebo-Controlled, Crossover Pilot Study.Cannabis (Albuquerque, N.M.) · 2023Article
- Article
- Substance use and pre-hospital crash injury severity among U.S. older adults: A five-year national cross-sectional study.PloS one · 2023Article
- Examining impairment and kinetic patterns associated with recent use of hemp-derived ΔJournal of cannabis research · 2022Article
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Authors and funding
13 authors.
Funding
Abstract
aimWe conducted a responsibility analysis to determine whether drivers injured in motor vehicle collisions who test positive for Δ-9-tetrahydrocannabinol (THC) or other drugs are more likely to have contributed to the crash than those who test negative.
designProspective case-control study.
settingTrauma centres in British Columbia, Canada.
participantsInjured drivers who required blood tests for clinical purposes following a motor vehicle collision. MEASUREMENTS: Excess whole blood remaining after clinical use was obtained and broad-spectrum toxicology testing performed. The analysis quantified alcohol and THC and gave semiquantitative levels of other impairing drugs and medications. Police crash reports were analysed to determine which drivers contributed to the crash (responsible) and which were 'innocently involved' (non-responsible). We used unconditional logistic regression to determine the likelihood (odds ratio: OR) of crash responsibility in drivers with 0 < THC < 2 ng/ml, 2 ng/ml ≤ THC < 5 ng/ml and THC ≥ 5 ng/ml (all versus THC = 0 ng/ml). Risk estimates were adjusted for age, sex and presence of other impairing substances.
findingsWe obtained toxicology results on 3005 injured drivers and police reports on 2318. Alcohol was detected in 14.4% of drivers, THC in 8.3%, other drugs in 8.9% and sedating medications in 19.8%. There was no increased risk of crash responsibility in drivers with THC < 2 ng/ml or 2 ≤ THC < 5 ng/ml. In drivers with THC ≥ 5 ng/ml, the adjusted OR was 1.74 [95% confidence interval (CI) = 0.59-6.36; P = 0.35]. There was significantly increased risk of crash responsibility in drivers with blood alcohol concentration (BAC) ≥ 0.08% (OR = 6.00;95% CI = 3.87-9.75; P < 0.01), other recreational drugs detected (OR = 1.82;95% CI = 1.21-2.80; P < 0.01) or sedating medications detected (OR = 1.45; 95%CI = 1.11-1.91; P < 0.01).
conclusionsIn this sample of non-fatally injured motor vehicle drivers in British Columbia, Canada, there was no evidence of increased crash risk in drivers with Δ-9-tetrahydrocannabinol < 5 ng/ml and a statistically non-significant increased risk of crash responsibility (odds ratio = 1.74) in drivers with Δ-9-tetrahydrocannabinol ≥ 5 ng/ml.
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