Evidence map›Paper›PMID 31106398›Full record

ArticleEuropean journal of immunology2019

Divergent memory responses driven by adenoviral vectors are impacted by epitope competition.

Julia M Colston, Claire Hutchings, Senthil Chinnakannan, Andrew Highton, Christian Perez-Shibayama, Burkhard Ludewig, Paul Klenerman

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in European journal of immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 55% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 3 countries.

Julia M ColstonNuffield Department of Medicine, Peter Medawar Building for Pathogen Research, University of Oxford, Oxford, UK.ORCID 0000-0002-3337-2455
Claire HutchingsNuffield Department of Medicine, Peter Medawar Building for Pathogen Research, University of Oxford, Oxford, UK.
Senthil ChinnakannanNuffield Department of Medicine, Peter Medawar Building for Pathogen Research, University of Oxford, Oxford, UK.
Andrew HightonNuffield Department of Medicine, Peter Medawar Building for Pathogen Research, University of Oxford, Oxford, UK.
Christian Perez-ShibayamaInstitute of Immunobiology, Kantonsspital St. Gallen, St. Gallen, Switzerland.
Burkhard LudewigInstitute of Immunobiology, Kantonsspital St. Gallen, St. Gallen, Switzerland.
Paul KlenermanNuffield Department of Medicine, Peter Medawar Building for Pathogen Research, University of Oxford, Oxford, UK.
University of Oxford · GBKantonsspital St. Gallen · CH

Funding

Cancer Research UK 23521Wellcome Trust 099897/Z/12/AWellcome Trust 109965MAWellcome Trust 109965/Z/15/Z
6 · The paper itself

Abstract

Adenoviral vectors induce robust epitope-specific CD8

Indexed as

AdenoviridaeAnimalsAntigens, ViralCD8-Positive T-LymphocytesEpitopes, T-LymphocyteFemaleGenetic VectorsImmunodominant EpitopesImmunologic MemoryLymphocytic ChoriomeningitisLymphocytic choriomeningitis virusMiceMice, Inbred C57BLViral ProteinsAntigens, ViralEpitopes, T-LymphocyteImmunodominant EpitopesViral Proteinsadenoviral vectorsimmunoproteasomeLCMVmemory inflationminigenes

Identifiers

PMID31106398
PMCPMC6772135
OpenAlexW2945813719

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.