Evidence map›Paper›PMID 31106381›Full record

Trial reportSleep2019

Effects on resident work hours, sleep duration, and work experience in a randomized order safety trial evaluating resident-physician schedules (ROSTERS).

Laura K Barger, Jason P Sullivan, Terri Blackwell, Conor S O'Brien, Melissa A St Hilaire, Shadab A Rahman, Andrew J K Phillips, Salim Qadri, Kenneth P Wright, Jeffrey L Segar and 13 more

Registry-linked trialAbstract readMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in Sleep, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02134847 (Multi-center Clinical Trial of Limiting Resident Work Hours on ICU Patient Safety), which is not on this map. Cited by 24 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02134847 nacompletednot on this map

Multi-center Clinical Trial of Limiting Resident Work Hours on ICU Patient Safety

TypeinterventionalSponsorBrigham and Women's HospitalRan2013 to 2017Enrolled413ConditionsPhysician FatigueArmsSCS intervention schedule
3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Insomnia-A Systematic Review and Comparison of Medical Resident's Average Off-Call Sleep Times.International journal of environmental research and public health · 2023
    Pooled it
  4. Trial
  5. Trial
  6. Article
  7. Article
  8. Impact of shift durations on sleep, fatigue, and wellness among neonatologists: a cross-sectional survey analysis.Journal of perinatology : official journal of the California Perinatal Association · 2025
    Article
  9. Article
  10. Article
  11. Sleep, chronotype, social jetlag, and mental health in resident physicians: a cross-sectional study.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2024
    Article
  12. Article
  13. Observational
  14. Article
  15. Article
  16. Review
  17. Review
  18. Article
  19. Objective Assessment of Sleep Patterns among Night-Shift Workers: A Scoping Review.International journal of environmental research and public health · 2021
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors.

Laura K BargerDepartment of Medicine and Neurology, Division of Sleep and Circadian Disorders, Brigham and Women's Hospital, Boston, MA.
Jason P SullivanDepartment of Medicine and Neurology, Division of Sleep and Circadian Disorders, Brigham and Women's Hospital, Boston, MA.
Terri BlackwellCalifornia Pacific Medical Center Research Institute, San Francisco, CA.
Conor S O'BrienDepartment of Medicine and Neurology, Division of Sleep and Circadian Disorders, Brigham and Women's Hospital, Boston, MA.
Melissa A St HilaireDepartment of Medicine and Neurology, Division of Sleep and Circadian Disorders, Brigham and Women's Hospital, Boston, MA.
Shadab A RahmanDepartment of Medicine and Neurology, Division of Sleep and Circadian Disorders, Brigham and Women's Hospital, Boston, MA.
Andrew J K PhillipsDepartment of Medicine and Neurology, Division of Sleep and Circadian Disorders, Brigham and Women's Hospital, Boston, MA.
Salim QadriDepartment of Medicine and Neurology, Division of Sleep and Circadian Disorders, Brigham and Women's Hospital, Boston, MA.
Kenneth P WrightSleep and Chronobiology Laboratory, Department of Integrative Physiology, University of Colorado Boulder, Boulder, CO.
Jeffrey L SegarUniversity of Iowa Stead Family Children's Hospital, Iowa City, IA.
John K McGuireSeattle Children's Hospital, Seattle, WA.
Michael V VitielloUniversity of Washington, Seattle, WA.
Horacio O de la IglesiaUniversity of Washington, Seattle, WA.
Sue E PoynterCincinnati Children's Hospital Medical Center, University of Cincinnati, Cincinnati, OH.
Pearl L YuUniversity of Virginia Children's Hospital, Charlottesville, VA.
Phyllis ZeeDepartment of Neurology, Northwestern University, Feinberg School of Medicine, Chicago, IL.
Amy L SandersonDivision of Critical Care Medicine, Department of Anesthesiology, Critical Care, and Pain Medicine, Boston Children's Hospital, Boston, MA.
Ann C HalbowerChildren's Hospital Colorado Anschutz Medical Campus, Aurora, CO.
Steven W LockleyDepartment of Medicine and Neurology, Division of Sleep and Circadian Disorders, Brigham and Women's Hospital, Boston, MA.
Christopher P LandriganDepartment of Medicine and Neurology, Division of Sleep and Circadian Disorders, Brigham and Women's Hospital, Boston, MA.
Katie L StoneCalifornia Pacific Medical Center Research Institute, San Francisco, CA.
Charles A CzeislerDepartment of Medicine and Neurology, Division of Sleep and Circadian Disorders, Brigham and Women's Hospital, Boston, MA.
ROSTERS Study Group

Funding

TRANSPLANTATION ANALYSIS OF CIRCADIAN RHYTHMS AND AGINGP01AG009975 · NIA · BRIGHAM AND WOMEN'S HOSPITAL · PI KLERMAN, ELIZABETH B. · 1991 to 2018
$23.1M
Multi-Center Trial of Limiting PGY2&3 Resident Work Hours on Patient Safety-CCCU01HL111478 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI CZEISLER, CHARLES A, LANDRIGAN, CHRISTOPHER PAUL · 2012 to 2017
$8.4M
Influence of sleep regularity on circadian rhythms, learning, performance, and moodR01HL128538 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI KLERMAN, ELIZABETH B. · 2016 to 2019
$3.6M
Sleep duration required to restore performance during chronic sleep restrictionR01HL114088 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI KLERMAN, ELIZABETH B. · 2012 to 2015
$3.1M
Impact of Eliminating Extended Duration Work Shifts on Resident Health and SafetyR01OH010300 · OH · BRIGHAM AND WOMEN'S HOSPITAL · PI BARGER, LAURA K. · 2013 to 2016
$2.8M
Multi-scale modeling of sleep behaviors in social networksR01GM105018 · NIGMS · BRIGHAM AND WOMEN'S HOSPITAL · PI CZEISLER, CHARLES A, KLERMAN, ELIZABETH B. · 2013 to 2017
$2.4M
MULTI-CENTER TRIAL OF LIMITING PGY2&3 RESIDENT WORK HOURS ON PATIENT SAFETY-DCCU01HL111691 · NHLBI · CALIFORNIA PACIFIC MED CTR RES INSTITUTE · PI STONE, KATIE L · 2012 to 2016
$1.9M
Sleep Duration Required to Restore Performance during Chronic Sleep RestrictionK24HL105664 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI KLERMAN, ELIZABETH B. · 2010 to 2019
$1.8M
Effects of Light and Melatonin on Contractions in Pregnant WomenR21HD086392 · NICHD · BRIGHAM AND WOMEN'S HOSPITAL · PI KLERMAN, ELIZABETH B. · 2016 to 2017
$488k
NHLBI NIH HHS K24 HL105664NHLBI NIH HHS R01 HL114088NHLBI NIH HHS R01 HL128538NHLBI NIH HHS U01 HL111478NHLBI NIH HHS U01 HL111691NIA NIH HHS P01 AG009975NICHD NIH HHS R21 HD086392NIGMS NIH HHS R01 GM105018NIOSH CDC HHS R01 OH010300NIOSH CDC HHS R01 OH011773
6 · The paper itself

Abstract

STUDY

objectivesWe compared resident physician work hours and sleep in a multicenter clustered-randomized crossover clinical trial that randomized resident physicians to an Extended Duration Work Roster (EDWR) with extended-duration (≥24 hr) shifts or a Rapidly Cycling Work Roster (RCWR), in which scheduled shift lengths were limited to 16 or fewer consecutive hours.

methodsThree hundred two resident physicians were enrolled and completed 370 1 month pediatric intensive care unit rotations in six US academic medical centers. Sleep was objectively estimated with wrist-worn actigraphs. Work hours and subjective sleep data were collected via daily electronic diary.

resultsResident physicians worked fewer total hours per week during the RCWR compared with the EDWR (61.9 ± 4.8 versus 68.4 ± 7.4, respectively; p < 0.0001). During the RCWR, 73% of work hours occurred within shifts of ≤16 consecutive hours. In contrast, during the EDWR, 38% of work hours occurred on shifts of ≤16 consecutive hours. Resident physicians obtained significantly more sleep per week on the RCWR (52.9 ± 6.0 hr) compared with the EDWR (49.1 ± 5.8 hr, p < 0.0001). The percentage of 24 hr intervals with less than 4 hr of actigraphically measured sleep was 9% on the RCWR and 25% on the EDWR (p < 0.0001).

conclusionsRCWRs were effective in reducing weekly work hours and the occurrence of >16 consecutive hour shifts, and improving sleep duration of resident physicians. Although inclusion of the six operational healthcare sites increases the generalizability of these findings, there was heterogeneity in schedule implementation. Additional research is needed to optimize scheduling practices allowing for sufficient sleep prior to all work shifts.Clinical Trial: Multicenter Clinical Trial of Limiting Resident Work Hours on ICU Patient Safety (ROSTERS), https://clinicaltrials.gov/ct2/show/NCT02134847.

Indexed as

AdultCross-Over StudiesFemaleHumansInternship and ResidencyMalePatient SafetyRecordsShift Work ScheduleSleepWork Schedule Toleranceactigraphyfatiguemedical educationsleepsleep diarywork hours

Identifiers

PMID31106381
PMCPMC6685326

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.