Evidence map›Paper›PMID 31106284›Full record

ArticleCurrent opinion in biomedical engineering2018

Physiological effects of low-magnitude electric fields on brain activity: advances from

Julien Modolo, Yves Denoyer, Fabrice Wendling, Pascal Benquet

Abstract read
In one paragraph

Article in Current opinion in biomedical engineering, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Review
  10. Review
  11. Article
  12. Modelling acute and lasting effects of tDCS on epileptic activity.Journal of computational neuroscience · 2020
    Article
  13. Review
  14. Current challenges: the ups and downs of tACS.Experimental brain research · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Julien ModoloInserm, Univ Rennes, LTSI - UMR 1099, F-35000 Rennes, France.
Yves DenoyerInserm, Univ Rennes, LTSI - UMR 1099, F-35000 Rennes, France.
Fabrice WendlingInserm, Univ Rennes, LTSI - UMR 1099, F-35000 Rennes, France.
Pascal BenquetInserm, Univ Rennes, LTSI - UMR 1099, F-35000 Rennes, France.

Funding

Manipulating multisite endogenous brain rhythms disrupts epileptic seizuresR01NS092760 · NINDS · ILLINOIS INSTITUTE OF TECHNOLOGY · PI MOGUL, DAVID J · 2016 to 2020
$1.3M
NINDS NIH HHS R01 NS092760
6 · The paper itself

Abstract

While electrical stimulation of brain tissue has been thoroughly investigated over the last decades, ongoing questions remain regarding the neurophysiological effects of low-level electric fields (on the order of 1 V/m) on brain activity. Electric fields at such levels are, for example, induced by transcranial direct/alternating current stimulation (tDCS/tACS). Action potentials can be indeed elicited when applied (supra-threshold) electric fields are in the 10-100 V/m range, while lower (subthreshold) electric fields result in more limited and subtler membrane polarization effects. In this review, we address the question of the mechanisms underlying the immediate effects (also referred to as acute, concurrent or short-term) and the lasting effects (also referred to as long-term or aftereffects) of low-level electric fields on brain tissue. We review recent evidence at the

Indexed as

computationalElectric fieldselectrophysiologyin vitroin vivomodeltranscranial alternating current stimulation (tACS)transcranial direct current stimulation (tDCS)

Identifiers

PMID31106284
PMCPMC6516771

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.