Evidence map›Paper›PMID 31106273›Full record

ArticleScience advances2019

Layer-specific activation of sensory input and predictive feedback in the human primary somatosensory cortex.

Yinghua Yu, Laurentius Huber, Jiajia Yang, David C Jangraw, Daniel A Handwerker, Peter J Molfese, Gang Chen, Yoshimichi Ejima, Jinglong Wu, Peter A Bandettini

Open access · goldAbstract read
In one paragraph

Article in Science advances, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed
5.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 97 citations in OpenAlex.

  1. Article
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  9. Metacognitive Feelings: A Predictive-Processing Perspective.Perspectives on psychological science : a journal of the Association for Psychological Science · 2025
    Review
  10. Article
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  15. High-resolution awake mouse fMRI at 14 Tesla.bioRxiv : the preprint server for biology · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Yinghua YuGraduate School of Interdisciplinary Science and Engineering in Health Systems, Okayama University, Okayama, Japan.
Laurentius HuberSection on Functional Imaging Methods, National Institute of Mental Health, Bethesda, MD, USA.ORCID 0000-0002-3291-2202
Jiajia YangGraduate School of Interdisciplinary Science and Engineering in Health Systems, Okayama University, Okayama, Japan.
David C JangrawSection on Functional Imaging Methods, National Institute of Mental Health, Bethesda, MD, USA.ORCID 0000-0002-2470-7647
Daniel A HandwerkerSection on Functional Imaging Methods, National Institute of Mental Health, Bethesda, MD, USA.ORCID 0000-0001-7261-4042
Peter J MolfeseSection on Functional Imaging Methods, National Institute of Mental Health, Bethesda, MD, USA.ORCID 0000-0002-3045-9408
Gang ChenScientific and Statistical Computing Core, National Institute of Mental Health, Bethesda, MD, USA.ORCID 0000-0002-2960-089X
Yoshimichi EjimaGraduate School of Interdisciplinary Science and Engineering in Health Systems, Okayama University, Okayama, Japan.
Jinglong WuGraduate School of Interdisciplinary Science and Engineering in Health Systems, Okayama University, Okayama, Japan.
Peter A BandettiniSection on Functional Imaging Methods, National Institute of Mental Health, Bethesda, MD, USA.
National Institute of Mental Health · USOkayama University · JP

Funding

Functional MRI Method DevelopmentZIAMH002783 · NIMH · NATIONAL INSTITUTE OF MENTAL HEALTH · PI BANDETTINI, PETER · 2009 to 2025
$38.4M
Intramural NIH HHS ZIA MH002783
6 · The paper itself

Abstract

When humans perceive a sensation, their brains integrate inputs from sensory receptors and process them based on their expectations. The mechanisms of this predictive coding in the human somatosensory system are not fully understood. We fill a basic gap in our understanding of the predictive processing of somatosensation by examining the layer-specific activity in sensory input and predictive feedback in the human primary somatosensory cortex (S1). We acquired submillimeter functional magnetic resonance imaging data at 7T (

Indexed as

Magnetic Resonance ImagingTouchAdultBrainBrain MappingFemaleHumansLinear ModelsMaleMiddle AgedMotionSomatosensory CortexYoung Adult

Identifiers

PMID31106273
PMCPMC6520017
OpenAlexW2946484570

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.