ArticleJournal of the Korean Association of Oral and Maxillofacial Surgeons2019
An experimental investigation of the effects of chronic stress on bone-to-implant contact.
Article in Journal of the Korean Association of Oral and Maxillofacial Surgeons, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed, 2 citations in OpenAlex.
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Authors and funding
8 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesThis study aimed to investigate the effects of chronic restraint stress on the osseointegration of titanium implants. MATERIALS AND
methodsTwenty adult male Wistar albino rats were used in the study. After surgical insertion of titanium implants into the metaphyseal part of the tibial bone, rats were randomly divided into two groups: a control group (CNT group) and an experimental restraint stress group (RS group). In the CNT group, titanium implants were inserted surgically, and rats received no further treatment during the 47-day experimental period. In the RS group, restraint stress was applied for 3 hours per day for 45 days, beginning 2 days after implant surgery. Weight of the rats was measured prior to surgery and at the end of the study to analyze the effects of stress. At the end of the experimental period, rats were euthanized, and implants and surrounding bone tissues were used for undecalcified histological analysis. Serum cortisol levels were assessed in cardiac blood samples from the rats following centrifugation.
resultsAverage weight of rats in the RS group was lower than that of rats in the CNT group after the experimental protocol had been completed (
conclusionThe data analyzed in this study suggest that chronic restraint stress did not adversely affect rats during a 45-day osseointegration period.
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