ArticleBioscience of microbiota, food and health2019
High-fat diet reduces the level of secretory immunoglobulin A coating of commensal gut microbiota.
Article in Bioscience of microbiota, food and health, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed.
- Added γ-oryzanol boosted anti-inflammatory effects of canola oil in adult subjects with type 2 diabetes: a randomized controlled clinical trial.European journal of nutrition · 2024Trial
- The gut microbiota and kawasaki disease: exploring the role of microbial dysbiosis and metabolites in pathogenesis and therapeutics.European journal of pediatrics · 2026Review
- Minimal Association Between Immunoglobulin A Coating and Gut Microbiota Alterations Induced by High-Fat Diets with Distinct Fatty Acid Compositions.International journal of molecular sciences · 2026Article
- Colonic inflammation triggers β cell proliferation during obesity development via a liver-to-pancreas interorgan mechanism.JCI insight · 2025Article
- Interplay of gut microbiota in Kawasaki disease: role of gut microbiota and potential treatment strategies.Future microbiology · 2025Review
- Extraction, Characterization, and Antioxidant Activity ofMolecules (Basel, Switzerland) · 2024Article
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- Exploration of theNutrients · 2024Review
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- Where Do We Stand in the Behavioral Pathogenesis of Inflammatory Bowel Disease? The Western Dietary Pattern and Microbiota-A Narrative Review.Nutrients · 2022Review
- Intestinal Barrier and Permeability in Health, Obesity and NAFLD.Biomedicines · 2021Review
- Article
- Diversity and dynamism of IgA-microbiota interactions.Nature reviews. Immunology · 2021Review
- Leaky Gut: Effect of Dietary Fiber and Fats on Microbiome and Intestinal Barrier.International journal of molecular sciences · 2021Review
- Review
- Ingestion of High β-Glucan Barley Flour Enhances the Intestinal Immune System of Diet-Induced Obese Mice by Prebiotic Effects.Nutrients · 2021Article
- High-Fat Diet and Age-Dependent Effects of IgA-Bearing Cell Populations in the Small Intestinal Lamina Propria in Mice.International journal of molecular sciences · 2021Article
- The Role of Diet in the Pathogenesis and Management of Inflammatory Bowel Disease: A Review.Nutrients · 2020Review
- Consumption of a high energy density diet triggers microbiota dysbiosis, hepatic lipidosis, and microglia activation in the nucleus of the solitary tract in rats.Nutrition & diabetes · 2020Article
- Variable selection in microbiome compositional data analysis.NAR genomics and bioinformatics · 2020Article
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Authors and funding
5 authors.
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Abstract
Excessive fat intake is associated with changes in gut microbiota composition. In the present study, we focused on the secretory immunoglobulin A (SIgA) coating of gut microbiota as a mucosal immune response affecting the gut microbiota following a high-fat diet (HFD). The level of SIgA coating of gut microbiota was evaluated in normal-fat diet (NFD)- and HFD-fed mice. HFD significantly decreased the level of SIgA coating the gut microbiota compared with NFD. Of note, substitution of HFD with NFD resulted in a complete recovery of the level of SIgA coating. These findings suggest that dietary fat influences the SIgA coating of the gut microbiota. Furthermore, we analyzed the composition of the gut microbiota and the concentration of cecal short-chain fatty acids. HFD feeding changed the gut microbiota composition at the phylum and family levels. Pearson correlation analysis between the level of SIgA coating of gut microbiota and the relative abundance of gut microbiota showed that the relative abundances of
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