ArticleDermatology practical & conceptual2019
Nonsurgical Options for the Treatment of Basal Cell Carcinoma.
Article in Dermatology practical & conceptual, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 45 citations in OpenAlex.
- Reflectance Confocal Microscopy-Optical Coherence Tomography-Guided Laser Ablation of Low-Risk Basal Cell Carcinoma: A Long-Term Prospective Follow-Up Study.Lasers in surgery and medicine · 2026Article
- Safe Use of Adrenaline in Cryosurgery for Eyelid Basal Cell Carcinoma Evaluated With Infrared Thermography.International wound journal · 2026Article
- Assessment of high- and low-risk histopathologic subtypes of basal cell carcinoma using artificial intelligence and dermatologist evaluation.JAAD international · 2026Article
- Beyond the scalpel: rare and experimental nonsurgical treatments for basal cell carcinoma.Dermatology online journal · 2026Review
- High-Intensity Focused Ultrasound in Dermatology: A Review with Emphasis on Skin Cancer Management and Prevention.Cancers · 2025Review
- Translational Potential of Fluorescent PARP1 Inhibitor as a Molecular Contrast Agent for Diagnosis of Basal Cell Carcinoma.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2025Article
- Therapeutic Approaches for Non-Melanoma Skin Cancer: Standard of Care and Emerging Modalities.International journal of molecular sciences · 2024Review
- Pilot Study on High-Intensity Focused Ultrasound (HIFU) for Basal Cell Carcinoma: Effectiveness and Safety.Journal of clinical medicine · 2024Article
- Photodynamic Therapy in Pigmented Basal Cell Carcinoma-A Review.Biomedicines · 2023Review
- Recommendations for Cost-Conscious Treatment of Basal Cell Carcinoma.Dermatology and therapy · 2023Review
- Topical Treatments for Basal Cell Carcinoma and Actinic Keratosis in the United States.Cancers · 2023Review
- Early clinical experience with a degraded 4 MeV electron beam in radiotherapy of superficial basal cell carcinoma.Physics and imaging in radiation oncology · 2023Article
- Basal Cell Carcinoma Perineural Invasion and Suggestive Signs of Perineural Invasion-Findings and Perspectives.Life (Basel, Switzerland) · 2023Article
- Pulsed Dye Laser for Treatment of Basal Cell Carcinoma.Plastic and reconstructive surgery. Global open · 2023Article
- Cryosurgery of Periocular Moderately Aggressive Basal Cell Carcinoma.Acta dermato-venereologica · 2020Article
- Superficial Basal Cell Carcinoma of the Face Successfully Treated with Ingenol Mebutate 0.05% Gel: Case Report and a Review of the Literature.The Journal of clinical and aesthetic dermatology · 2020Article
- Imiquimod does not elicit inflammatory responses in the skin of the naked mole rat (Heterocephalus glaber).BMC research notes · 2020Article
- [Therapeutic alternatives to surgical treatment of malignant eyelid tumors and their precursors].Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft · 2020Review
- Basal Cell Carcinoma Surgery in general practice: Is there a role for the local General Practitioner?Malaysian family physician : the official journal of the Academy of Family Physicians of Malaysia · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesThe aim of this review article is to summarize the effectiveness, potential adverse events, and indications of the main nonsurgical treatment alternatives for basal cell carcinoma.
methodsAn extensive literature review was carried out. The most relevant articles were discussed and selected by the authors in order to provide a brief but evidence-based overview of the most common nonsurgical methods used for treating basal cell carcinoma.
resultsAlthough surgery and Mohs micrographic surgery are often considered the optimal treatment options for basal cell carcinoma, these tumors can also be treated successfully with destructive techniques (eg, curettage alone, cryosurgery, or electrodesiccation), photodynamic therapy, topical drugs (eg, 5-fluorouracil, imiquimod, or ingenol mebutate), radiotherapy, or hedgehog pathway inhibitors. When choosing between these alternatives, physicians must take into consideration the tumor's size, location, and histopathological subtype. Special care should be taken when treating recurrent tumors. Furthermore, physician experience is of great importance when using destructive techniques. Finally, patient preference, potential adverse events, and cosmetic outcome should also be considered.
conclusionsDermatologists and physicians treating basal cell carcinoma should have knowledge of and experience with the large arsenal of therapeutic alternatives available for the successful, safe, and individualized management of patients with basal cell carcinoma.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.