Immune response evoked by tumor-associated NADH oxidase (tNOX) confers potential inhibitory effect on lung carcinoma in a mouse model.

Pei-Fang Hsieh, Pin Ju Chueh, Pei-Fen Liu, Jiunn-Wang Liao, Ming-Kun Hsieh

Open access · greenAbstract read

In one paragraph

Article in American journal of cancer research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

0.5field-weighted citation impact, top 33% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

Targeting Glioblastoma via Selective Alteration of Mitochondrial Redox State.Cancers · 2022
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Pei-Fang HsiehGraduate Institute of Microbiology and Public Health, National Chung Hsing University Taichung 40227, Taiwan.

Pin Ju ChuehInstitute of Biomedical Sciences, National Chung Hsing University Taichung 40227, Taiwan.

Pei-Fen LiuDepartment of Food Science and Biotechnology, National Chung Hsing University Taichung 40227, Taiwan.

Jiunn-Wang LiaoGraduate Institute of Veterinary Pathobiology, National Chung Hsing University Taichung 40227, Taiwan.

Ming-Kun HsiehGraduate Institute of Microbiology and Public Health, National Chung Hsing University Taichung 40227, Taiwan.

National Chung Hsing University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tumor-associated NADH oxidase (tNOX, ENOX2), which belongs to a family of growth-related NADH oxidases, was originally identified as a plasma membrane protein of rat hepatoma and is inhibited or downregulated by several anti-cancer drugs. The objective of this study was to evaluate the anti-tumor effects of tNOX used as an immunogen against Lewis lung cancer. Human tNOX was expressed in

Indexed as

biomarkercancer immunotherapyENOX2)tumor-associated antigen (TAA)Tumor-associated NADH oxidase (tNOX

Identifiers

PMID31106000

PMCPMC6511635

OpenAlexW3016403499

What OpenQuestion holds

Textmetadata

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.