Evidence map›Paper›PMID 31105899›Full record

ArticleNano research2018

Advances in Nanomaterials for Brain Microscopy.

Jackson Travis Del Bonis-O'Donnell, Linda Chio, Gabriel F Dorlhiac, Ian R McFarlane, Markita P Landry

Open access · hybridAbstract read
In one paragraph

Article in Nano research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Fluorescent spScientific reports · 2020
    Article
  5. Near-Infrared-II Molecular Dyes for Cancer Imaging and Surgery.Advanced materials (Deerfield Beach, Fla.) · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Jackson Travis Del Bonis-O'DonnellDepartment of Chemical and Biomolecular Engineering, University of California, Berkeley, CA 94720.
Linda ChioDepartment of Chemical and Biomolecular Engineering, University of California, Berkeley, CA 94720.
Gabriel F DorlhiacDepartment of Chemical and Biomolecular Engineering, University of California, Berkeley, CA 94720.
Ian R McFarlaneDepartment of Chemical and Biomolecular Engineering, University of California, Berkeley, CA 94720.
Markita P LandryDepartment of Chemical and Biomolecular Engineering, University of California, Berkeley, CA 94720.
University of California, Berkeley · USInnovative Genomics Institute · US

Funding

Optical montoring of modulatory neurotransmitter levels using new infrared nanonsensorsR21DA044010 · NIDA · UNIVERSITY OF CALIFORNIA BERKELEY · PI WILBRECHT, LINDA E · 2017 to 2018
$323k
NIDA NIH HHS R21 DA044010
6 · The paper itself

Abstract

Microscopic imaging of the brain continues to reveal details of its structure, connectivity, and function. To further improve our understanding of the emergent properties and functions of neural circuits, new methods are necessary to directly visualize the relationship between brain structure, neuron activity, and neurochemistry. Advances in engineering the chemical and optical properties of nanomaterials concurrent with developments in deep-tissue microscopy hold tremendous promise for overcoming the current challenges associated with in vivo brain imaging, particularly for imaging the brain through optically-dense brain tissue, skull, and scalp. To this end, developments in nanomaterials offer much promise toward implementing tunable chemical functionality for neurochemical targeting and sensing, and fluorescence stability for long-term imaging. In this review, we summarize current brain microscopy methods and describe the diverse classes of nanomaterials recently leveraged as contrast agents and functional probes for microscopic optical imaging of the brain.

Identifiers

PMID31105899
PMCPMC6516768
OpenAlexW2886422707

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.