Evidence map›Paper›PMID 31105707›Full record

ReviewFrontiers in immunology2019

Innate Lymphoid Cells: Expression of PD-1 and Other Checkpoints in Normal and Pathological Conditions.

Francesca Romana Mariotti, Linda Quatrini, Enrico Munari, Paola Vacca, Lorenzo Moretta

Abstract readReview
In one paragraph

Review in Frontiers in immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
51citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

51 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Resisting Resistance to Immune Checkpoint Therapy: A Systematic Review.International journal of molecular sciences · 2020
    Pooled it
  3. Trial
  4. IDH1 Mutant Glioma Favors Group 3 Innate Lymphoid Cells and Is Resistant to Immune Checkpoint Expression.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2026
    Article
  5. Review
  6. Article
  7. Review
  8. Article
  9. Early-life human CD8Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  10. Modulating the PD-1-FABP5 axis in ILC2s to regulate adipose tissue metabolism in obesity.Molecular therapy : the journal of the American Society of Gene Therapy · 2025
    Article
  11. Restriction of innate Tγδ17 cell plasticity by an AP-1 regulatory axis.bioRxiv : the preprint server for biology · 2024
    Article
  12. Review
  13. Article
  14. Article
  15. Review
  16. Review
  17. Review
  18. [Research progress on the role of type II innate lymphoid cells in liver diseases].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2023
    Review
  19. Checkpoint Inhibitor-Induced Colitis: From Pathogenesis to Management.International journal of molecular sciences · 2023
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Francesca Romana MariottiDepartment of Immunology, IRCSS Bambino Gesù Children's Hospital, Rome, Italy.
Linda QuatriniDepartment of Immunology, IRCSS Bambino Gesù Children's Hospital, Rome, Italy.
Enrico MunariDepartment of Pathology, Sacro Cuore Don Calabria Hospital, Negrar, Italy.
Paola VaccaDepartment of Immunology, IRCSS Bambino Gesù Children's Hospital, Rome, Italy.
Lorenzo MorettaDepartment of Immunology, IRCSS Bambino Gesù Children's Hospital, Rome, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Innate lymphoid cells (ILCs) belong to a family of immune cells. Recently, ILCs have been classified into five different groups that mirror the function of adaptive T cell subsets counterparts. In particular, NK cells mirror CD8

Indexed as

Hepatitis A Virus Cellular Receptor 2HumansImmunity, InnateKiller Cells, NaturalLymphoid TissueNeoplasmsProgrammed Cell Death 1 ReceptorReceptors, ImmunologicT-Lymphocytes, CytotoxicT-Lymphocytes, Helper-InducerTumor EscapeHAVCR2 protein, humanHepatitis A Virus Cellular Receptor 2PDCD1 protein, humanProgrammed Cell Death 1 ReceptorReceptors, ImmunologicTIGIT protein, humancancer immunotherapiescheckpoint receptorsILCNKPD-1

Identifiers

PMID31105707
PMCPMC6498986

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.