Evidence map›Paper›PMID 31105698›Full record

ArticleFrontiers in immunology2019

Gene Expression Signatures Associated With Immune and Virological Responses to Therapeutic Vaccination With Dendritic Cells in HIV-Infected Individuals.

Rodolphe Thiébaut, Boris P Hejblum, Hakim Hocini, Henri Bonnabau, Jason Skinner, Monica Montes, Christine Lacabaratz, Laura Richert, Karolina Palucka, Jacques Banchereau and 1 more

Open access · goldAbstract readClinical Trial, Phase I
In one paragraph

Article in Frontiers in immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.4field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Rodolphe ThiébautInserm, Bordeaux Population Health Research Center, UMR 1219, Univ. Bordeaux, ISPED, Bordeaux, France.
Boris P HejblumInserm, Bordeaux Population Health Research Center, UMR 1219, Univ. Bordeaux, ISPED, Bordeaux, France.
Hakim HociniVACCINE RESEARCH INSTITUTE - VRI, Groupe Henri-Mondor Albert-Chenevier, Créteil, France.
Henri BonnabauInserm, Bordeaux Population Health Research Center, UMR 1219, Univ. Bordeaux, ISPED, Bordeaux, France.
Jason SkinnerBaylor Institute for Immunology Research, Ralph Steinman Center for Cancer Vaccines, Dallas, TX, United States.
Monica MontesBaylor Institute for Immunology Research, Ralph Steinman Center for Cancer Vaccines, Dallas, TX, United States.
Christine LacabaratzVACCINE RESEARCH INSTITUTE - VRI, Groupe Henri-Mondor Albert-Chenevier, Créteil, France.
Laura RichertInserm, Bordeaux Population Health Research Center, UMR 1219, Univ. Bordeaux, ISPED, Bordeaux, France.
Karolina PaluckaBaylor Institute for Immunology Research, Ralph Steinman Center for Cancer Vaccines, Dallas, TX, United States.
Jacques BanchereauBaylor Institute for Immunology Research, Ralph Steinman Center for Cancer Vaccines, Dallas, TX, United States.
Yves LévyVACCINE RESEARCH INSTITUTE - VRI, Groupe Henri-Mondor Albert-Chenevier, Créteil, France.
Institut de Recherche Vaccinale · FRBordeaux Population Health · FRInserm · FRUniversité de Bordeaux · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The goal of HIV therapeutic vaccination is to induce HIV-specific immune response able to control HIV replication. We previously reported that vaccination with

Indexed as

TranscriptomeAdultAIDS VaccinesBlood CellsComputational BiologyCytokinesDendritic CellsFemaleGene Expression ProfilingHIV-1HIV AntigensHIV InfectionsHost-Pathogen InteractionsHumansMaleMiddle AgedAIDS VaccinesCytokinesHIV Antigensantiretroviral therapy interruptiondendritic cellgene expressionHIVsystems biologytherapeutic vaccine

Identifiers

PMID31105698
PMCPMC6492565
OpenAlexW2940763747

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.