Evidence map›Paper›PMID 31105663›Full record

ArticleFrontiers in microbiology2019

Human, Nonhuman Primate, and Bat Cells Are Broadly Susceptible to Tibrovirus Particle Cell Entry.

Yíngyún Caì, Shuǐqìng Yú, Rohit K Jangra, Elena N Postnikova, Jiro Wada, Robert B Tesh, Sean P J Whelan, Michael Lauck, Michael R Wiley, Courtney L Finch and 6 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in microbiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.9field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 8 institutions in 1 country.

Yíngyún CaìIntegrated Research Facility at Fort Detrick, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Frederick, MD, United States.
Shuǐqìng YúIntegrated Research Facility at Fort Detrick, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Frederick, MD, United States.
Rohit K JangraDepartment of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY, United States.
Elena N PostnikovaIntegrated Research Facility at Fort Detrick, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Frederick, MD, United States.
Jiro WadaIntegrated Research Facility at Fort Detrick, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Frederick, MD, United States.
Robert B TeshDepartment of Pathology, Center for Biodefense and Emerging Infectious Diseases, The University of Texas Medical Branch, Galveston, TX, United States.
Sean P J WhelanDepartment of Microbiology and Immunobiology, Harvard Medical School, Boston, MA, United States.
Michael LauckDepartment of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, WI, United States.
Michael R WileyUnited States Army Medical Research Institute of Infectious Diseases, Frederick, MD, United States.
Courtney L FinchIntegrated Research Facility at Fort Detrick, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Frederick, MD, United States.
Sheli R RadoshitzkyUnited States Army Medical Research Institute of Infectious Diseases, Frederick, MD, United States.
David H O'ConnorDepartment of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, WI, United States.
Gustavo PalaciosUnited States Army Medical Research Institute of Infectious Diseases, Frederick, MD, United States.
Kartik ChandranDepartment of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY, United States.
Charles Y ChiuDivision of Infectious Diseases, University of California, San Francisco, San Francisco, CA, United States.
Jens H KuhnIntegrated Research Facility at Fort Detrick, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Frederick, MD, United States.
National Institutes of Health · USUnited States Army Medical Research Institute of Infectious Diseases · USAlbert Einstein College of Medicine · USNational Institute of Allergy and Infectious Diseases · USUniversity of Wisconsin–Madison · USHarvard University · USThe University of Texas Medical Branch at Galveston · USUniversity of California, San Francisco · US

Funding

Dissecting the receptor-mediated infection mechanisms of hantavirusesR01AI132633 · NIAID · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI CHANDRAN, KARTIK · 2017 to 2021
$3.2M
NIAID NIH HHS HHSN272200700016INIAID NIH HHS R01 AI132633
6 · The paper itself

Abstract

In 2012, the genome of a novel rhabdovirus, Bas-Congo virus (BASV), was discovered in the acute-phase serum of a Congolese patient with presumed viral hemorrhagic fever. In the absence of a replicating virus isolate, fulfilling Koch's postulates to determine whether BASV is indeed a human virus and/or pathogen has been impossible. However, experiments with vesiculoviral particles pseudotyped with Bas-Congo glycoprotein suggested that BASV particles can enter cells from multiple animals, including humans. In 2015, genomes of two related viruses, Ekpoma virus 1 (EKV-1) and Ekpoma virus 2 (EKV-2), were detected in human sera in Nigeria. Isolates could not be obtained. Phylogenetic analyses led to the classification of BASV, EKV-1, and EKV-2 in the same genus,

Indexed as

Bas-Congo virusMononegaviralesmononegavirusRhabdoviridaerhabdovirustibrovirustropismviral hemorrhagic fever

Identifiers

PMID31105663
PMCPMC6499107
OpenAlexW2949702594

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.