Evidence map›Paper›PMID 31105594›Full record

ArticleFrontiers in physiology2019

Neuromuscular and Muscle Metabolic Functions in MELAS Before and After Resistance Training: A Case Study.

Massimo Venturelli, Federica Villa, Federico Ruzzante, Cantor Tarperi, Doriana Rudi, Chiara Milanese, Valentina Cavedon, Cristina Fonte, Alessandro Picelli, Nicola Smania and 4 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in physiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.4field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Electrically induced quadriceps fatigue in the contralateral leg impairs ipsilateral knee extensors performance.American journal of physiology. Regulatory, integrative and comparative physiology · 2021
    Article
  5. Article
  6. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 2 countries.

Massimo VenturelliDepartment of Neurosciences, Biomedicine and Movement Sciences, University of Verona, Verona, Italy.
Federica VillaDepartment of Neurosciences, Biomedicine and Movement Sciences, University of Verona, Verona, Italy.
Federico RuzzanteDepartment of Neurosciences, Biomedicine and Movement Sciences, University of Verona, Verona, Italy.
Cantor TarperiDepartment of Neurosciences, Biomedicine and Movement Sciences, University of Verona, Verona, Italy.
Doriana RudiDepartment of Neurosciences, Biomedicine and Movement Sciences, University of Verona, Verona, Italy.
Chiara MilaneseDepartment of Neurosciences, Biomedicine and Movement Sciences, University of Verona, Verona, Italy.
Valentina CavedonDepartment of Neurosciences, Biomedicine and Movement Sciences, University of Verona, Verona, Italy.
Cristina FonteNeuromotor and Cognitive Rehabilitation Research Centre, Department of Neuroscience, Biomedicine and Movement Sciences, University of Verona, Verona, Italy.
Alessandro PicelliNeuromotor and Cognitive Rehabilitation Research Centre, Department of Neuroscience, Biomedicine and Movement Sciences, University of Verona, Verona, Italy.
Nicola SmaniaNeuromotor and Cognitive Rehabilitation Research Centre, Department of Neuroscience, Biomedicine and Movement Sciences, University of Verona, Verona, Italy.
Elisa CalabriaDepartment of Neurosciences, Biomedicine and Movement Sciences, University of Verona, Verona, Italy.
Spyros SkafidasDepartment of Neurosciences, Biomedicine and Movement Sciences, University of Verona, Verona, Italy.
Gwenael LayecDepartment of Kinesiology, University of Massachusetts, Amherst MA, United States.
Federico SchenaDepartment of Neurosciences, Biomedicine and Movement Sciences, University of Verona, Verona, Italy.
University of Verona · ITUniversity of Massachusetts Amherst · USUniversity of Utah · US

Funding

Nitric oxide coupling and BH4 availability roles in muscle dysfunction with COPDR00HL125756 · NHLBI · UNIVERSITY OF MASSACHUSETTS AMHERST · PI LAYEC, GWENAEL · 2018 to 2020
$738k
Nitric oxide coupling and BH4 availability roles in muscle dysfunction with COPDK99HL125756 · NHLBI · UNIVERSITY OF UTAH · PI LAYEC, GWENAEL · 2015 to 2016
$300k
NHLBI NIH HHS K99 HL125756NHLBI NIH HHS R00 HL125756
6 · The paper itself

Abstract

Mitochondrial encephalomyopathy, lactic acidosis, and recurrent stroke-like episodes syndrome (MELAS) is a rare degenerative disease. Recent studies have shown that resistant training (RT) can ameliorate muscular force in mitochondrial diseases. However, the effects of RT in MELAS are unknown. The aim of this case report was to investigate the effects of RT on skeletal muscle and mitochondrial function in a 21-years old patient with MELAS. RT included 12 weeks of RT at 85% of 1 repetition maximum. Body composition (DXA),

Indexed as

exerciseMELASmuscle respiratory capacityneuromuscular functionresistance training

Identifiers

PMID31105594
PMCPMC6498991
OpenAlexW2940680854

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.