Evidence map›Paper›PMID 31105467›Full record

ArticleGenetic programming and evolvable machines2019

Automated discovery of test statistics using genetic programming.

Jason H Moore, Randal S Olson, Yong Chen, Moshe Sipper

Abstract read
In one paragraph

Article in Genetic programming and evolvable machines, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jason H Moore *Institute for Biomedical Informatics, Perelman School of Medicine, University of Pennsylvania, Philadelphia PA 19104, USA.
Randal S Olson *Institute for Biomedical Informatics, Perelman School of Medicine, University of Pennsylvania, Philadelphia PA 19104, USA.
Yong ChenInstitute for Biomedical Informatics, Perelman School of Medicine, University of Pennsylvania, Philadelphia PA 19104, USA.
Moshe SipperInstitute for Biomedical Informatics, Perelman School of Medicine, University of Pennsylvania, Philadelphia PA 19104, USA.

Funding

Human Pancreas Analysis Program for Type 1 Diabetes - HPAP-T1DU01DK112217 · NIDDK · UNIVERSITY OF PENNSYLVANIA · PI MARK A. ATKINSON, KLAUS H KAESTNER · 2021 to 2026
$46.8M
Penn integrated Human Pancreas procurement and Analysis ProgramUC4DK112217 · NIDDK · UNIVERSITY OF PENNSYLVANIA · PI BETTS, MICHAEL R, FELDMAN, MICHAEL D · 2016 to 2020
$17.8M
Bioinformatics Strategies for Genome-Wide Association StudiesR01LM010098 · NLM · UNIVERSITY OF PENNSYLVANIA · PI MOORE, JASON H., WILLIAMS, SCOTT MATTHEW · 2009 to 2023
$5.1M
Biomedical Computing and Informatics Strategies for Infectious Disease ResearchR01AI116794 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI MOORE, JASON H. · 2016 to 2020
$2.9M
Biomedical Computing and Informatics Strategies for Precision MedicineR01LM012601 · NLM · UNIVERSITY OF PENNSYLVANIA · PI HUANG, XIUZHEN, MOORE, JASON H. · 2017 to 2020
$1.8M
NIAID NIH HHS R01 AI116794NIDDK NIH HHS U01 DK112217NIDDK NIH HHS UC4 DK112217NLM NIH HHS R01 LM010098NLM NIH HHS R01 LM012601
6 · The paper itself

Abstract

The process of developing new test statistics is laborious, requiring the manual development and evaluation of mathematical functions that satisfy several theoretical properties. Automating this process, hitherto not done, would greatly accelerate the discovery of much-needed, new test statistics. This automation is a challenging problem because it requires the discovery method to know something about the desirable properties of a good test statistic in addition to having an engine that can develop and explore candidate mathematical solutions with an intuitive representation. In this paper we describe a genetic programming-based system for the automated discovery of new test statistics. Specifically, our system was able to discover test statistics as powerful as the t-test for comparing sample means from two distributions with equal variances.

Indexed as

Genetic ProgrammingOptimizationStatisticsT-Test

Identifiers

PMID31105467
PMCPMC6519943

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.