Evidence map›Paper›PMID 31105355›Full record

ArticleJournal of multivariate analysis2019

Sparse quadratic classification rules via linear dimension reduction.

Irina Gaynanova, Tianying Wang

Abstract read
In one paragraph

Article in Journal of multivariate analysis, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Irina GaynanovaDepartment of Statistics, Texas A&M University, 3143 TAMU, College Station, TX 77843, USA.
Tianying WangDepartment of Statistics, Texas A&M University, 3143 TAMU, College Station, TX 77843, USA.

Funding

Measurement Error, Nutrition, Physical Activity and CancerU01CA057030 · NCI · TEXAS A&M UNIVERSITY · PI CARROLL, RAYMOND J. · 2015 to 2019
$2.8M
NCI NIH HHS U01 CA057030
6 · The paper itself

Abstract

We consider the problem of high-dimensional classification between two groups with unequal covariance matrices. Rather than estimating the full quadratic discriminant rule, we propose to perform simultaneous variable selection and linear dimension reduction on the original data, with the subsequent application of quadratic discriminant analysis on the reduced space. In contrast to quadratic discriminant analysis, the proposed framework doesn't require the estimation of precision matrices; it scales linearly with the number of measurements, making it especially attractive for the use on high-dimensional datasets. We support the methodology with theoretical guarantees on variable selection consistency, and empirical comparisons with competing approaches. We apply the method to gene expression data of breast cancer patients, and confirm the crucial importance of the ESR1 gene in differentiating estrogen receptor status.

Indexed as

Convex optimizationDiscriminant analysisHigh-dimensional statisticsVariable selection

Identifiers

PMID31105355
PMCPMC6516858

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.