Evidence map›Paper›PMID 31105339›Full record

ArticlePattern recognition2019

Texture Analysis for Muscular Dystrophy Classification in MRI with Improved Class Activation Mapping.

Jinzheng Cai, Fuyong Xing, Abhinandan Batra, Fujun Liu, Glenn A Walter, Krista Vandenborne, Lin Yang

Open access · greenAbstract read
In one paragraph

Article in Pattern recognition, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.0field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 48 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Jinzheng CaiJ. Crayton Pruitt Family Department of Biomedical Engineering, University of Florida.
Fuyong XingDepartment of Biostatistics and Informatics, University of Colorado Denver.
Abhinandan BatraDepartment of Physiology and Functional Genomics, University of Florida.
Fujun LiuDepartment of Electrical and Computer Engineering, University of Florida.
Glenn A WalterDepartment of Physiology and Functional Genomics, University of Florida.
Krista VandenborneDepartment of Physical Therapy, University of Florida.
Lin YangJ. Crayton Pruitt Family Department of Biomedical Engineering, University of Florida.
University of Florida · USUniversity of Colorado Anschutz Medical Campus · US

Funding

Training and education CoreU54AR052646 · NIAMS · UNIVERSITY OF PENNSYLVANIA · PI MCNALLY, ELIZABETH M, SWEENEY, H LEE · 2005 to 2020
$24.1M
Magnetic Resonance Imaging and Biomarkers for Muscular DystropyR01AR056973 · NIAMS · UNIVERSITY OF FLORIDA · PI VANDENBORNE, KRISTA H · 2010 to 2024
$20.2M
Development and Dissemination of MuscleMiner: An Imaging Informatics Tool for MusR01AR065479 · NIAMS · UNIVERSITY OF FLORIDA · PI DING, MINGZHOU · 2014 to 2018
$1.8M
The Relationship between Genomic Variants and MRI/MRS Markers in DMDR01AR065943 · NIAMS · UNIVERSITY OF FLORIDA · PI WALTER, GLENN · 2013 to 2015
$998k
NIAMS NIH HHS R01 AR056973NIAMS NIH HHS R01 AR065479NIAMS NIH HHS R01 AR065943NIAMS NIH HHS U54 AR052646
6 · The paper itself

Abstract

The muscular dystrophies are made up of a diverse group of rare genetic diseases characterized by progressive loss of muscle strength and muscle damage. Since there is no cure for muscular dystrophy and clinical outcome measures are limited, it is critical to assess the progression of MD objectively. Imaging muscle replacement by fibrofatty tissue has been shown to be a robust biomarker to monitor disease progression in DMD. In magnetic resonance imaging (MRI) data, specific texture patterns are found to correlate to certain MD subtypes and thus present a potential way for automatic assessment. In this paper, we first apply state-of-the-art convolutional neural networks (CNNs) to perform accurate MD image classification and then propose an effective visualization method to highlight the important image textures. With a dystrophic MRI dataset, we found that the best CNN model delivers an 91.7% classification accuracy, which significantly outperforms non-deep learning methods,

Indexed as

abnormality detectionconvolutional neural networkMRI analysisMuscular dystrophytexture classification

Identifiers

PMID31105339
PMCPMC6521874
OpenAlexW2889649018

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.