Evidence map›Paper›PMID 31105210›Full record

ArticleBiomimetics (Basel, Switzerland)2019

Bioinspired Histidine⁻Zn

Isabell Tunn, Matthew J Harrington, Kerstin G Blank

Abstract read
In one paragraph

Article in Biomimetics (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Article
  2. Review
  3. On-Demand Chemically Degradable Hydrogels for Biological Applications.Chembiochem : a European journal of chemical biology · 2026
    Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Metal Ion-Induced Cross-Linking in Mucin-Inspired Peptide Hydrogels.Journal of peptide science : an official publication of the European Peptide Society · 2025
    Article
  9. Review
  10. Article
  11. Peptide-Based Materials That Exploit Metal Coordination.International journal of molecular sciences · 2022
    Review
  12. Review
  13. Review
  14. Review
  15. Article
  16. Article
  17. Thermo-Viscoelastic Response of Protein-Based Hydrogels.Bioengineering (Basel, Switzerland) · 2021
    Article
  18. Fortified Coiled Coils: Enhancing Mechanical Stability with Lactam or Metal Staples.Angewandte Chemie (International ed. in English) · 2021
    Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Isabell TunnMechano(bio)chemistry, Max Planck Institute of Colloids and Interfaces, Science Park Potsdam-Golm, 14424 Potsdam, Germany. Isabell.Tunn@mpikg.mpg.de.ORCID 0000-0003-0853-8908
Matthew J HarringtonDepartment of Biomaterials, Max Planck Institute of Colloids and Interfaces, Science Park Potsdam-Golm, 14424 Potsdam, Germany. Matt.Harrington@mcgill.ca.
Kerstin G BlankMechano(bio)chemistry, Max Planck Institute of Colloids and Interfaces, Science Park Potsdam-Golm, 14424 Potsdam, Germany. Kerstin.Blank@mpikg.mpg.de.ORCID 0000-0001-5410-6984

Funding

IMPRS on Multiscale Bio-Systems n.a.Max-Planck-Gesellschaft n.a.
6 · The paper itself

Abstract

Natural biopolymeric materials often possess properties superior to their individual components. In mussel byssus, reversible histidine (His)-metal coordination is a key feature, which mediates higher-order self-assembly as well as self-healing. The byssus structure, thus, serves as an excellent natural blueprint for the development of self-healing biomimetic materials with reversibly tunable mechanical properties. Inspired by byssal threads, we bioengineered His-metal coordination sites into a heterodimeric coiled coil (CC). These CC-forming peptides serve as a noncovalent cross-link for poly(ethylene glycol)-based hydrogels and participate in the formation of higher-order assemblies via intermolecular His-metal coordination as a second cross-linking mode. Raman and circular dichroism spectroscopy revealed the presence of α-helical, Zn

Indexed as

coiled coilhistidine–metal coordinationhydrogelrheologyself-healing

Identifiers

PMID31105210
PMCPMC6477626

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.