Evidence map›Paper›PMID 31105205›Full record

ReviewBiomimetics (Basel, Switzerland)2019

Healing through Histidine: Bioinspired Pathways to Self-Healing Polymers via Imidazole⁻Metal Coordination.

Stefan Zechel, Martin D Hager, Tobias Priemel, Matthew J Harrington

Open access · goldAbstract readReview
In one paragraph

Review in Biomimetics (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
5.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 87 citations in OpenAlex.

  1. Article
  2. Article
  3. Metal Ion-Induced Cross-Linking in Mucin-Inspired Peptide Hydrogels.Journal of peptide science : an official publication of the European Peptide Society · 2025
    Article
  4. Article
  5. Article
  6. Localization of ZnSoft matter · 2023
    Article
  7. Article
  8. Review
  9. Article
  10. ACS nano · 2021
    Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Stefan ZechelLaboratory for Organic and Macromolecular Chemistry (IOMC), Friedrich Schiller University Jena, Humboldtstr. 10, 07743 Jena, Germany. stefan.zechel@uni-jena.de.
Martin D HagerLaboratory for Organic and Macromolecular Chemistry (IOMC), Friedrich Schiller University Jena, Humboldtstr. 10, 07743 Jena, Germany. martin.hager@uni-jena.de.
Tobias PriemelDepartment of Chemistry, McGill University, 801 Sherbrooke Street West, Montreal, QC H3A 0B8, Canada. tobias.priemel@mail.mcgill.ca.
Matthew J HarringtonDepartment of Chemistry, McGill University, 801 Sherbrooke Street West, Montreal, QC H3A 0B8, Canada. matt.harrington@mcgill.ca.
Friedrich Schiller University Jena · DEMcGill University · CA

Funding

Natural Sciences and Engineering Research Council of Canada RGPIN-2018-05243
6 · The paper itself

Abstract

Biology offers a valuable inspiration toward the development of self-healing engineering composites and polymers. In particular, chemical level design principles extracted from proteinaceous biopolymers, especially the mussel byssus, provide inspiration for design of autonomous and intrinsic healing in synthetic polymers. The mussel byssus is an acellular tissue comprised of extremely tough protein-based fibers, produced by mussels to secure attachment on rocky surfaces. Threads exhibit self-healing response following an apparent plastic yield event, recovering initial material properties in a time-dependent fashion. Recent biochemical analysis of the structure-function relationships defining this response reveal a key role of sacrificial cross-links based on metal coordination bonds between Zn

Indexed as

histidinehydrogelsimidazolemetal coordinationmetallopolymersmussel byssusself-healing

Identifiers

PMID31105205
PMCPMC6477608
OpenAlexW2915725705

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.