Evidence map›Paper›PMID 31105189›Full record

ArticleBiomimetics (Basel, Switzerland)2019

NDs@PDA@ICG Conjugates for Photothermal Therapy of Glioblastoma Multiforme.

Damian Maziukiewicz, Bartosz F Grześkowiak, Emerson Coy, Stefan Jurga, Radosław Mrówczyński

Open access · goldAbstract read
In one paragraph

Article in Biomimetics (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 69 citations in OpenAlex.

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  12. Recent Developments of Nanodiamond Quantum Sensors for Biological Applications.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Damian MaziukiewiczNanoBioMedical Centre, Adam Mickiewicz University, ul. Umultowska 85, PL-61614 Poznań, Poland. damian.maziukiewicz@amu.edu.pl.
Bartosz F GrześkowiakNanoBioMedical Centre, Adam Mickiewicz University, ul. Umultowska 85, PL-61614 Poznań, Poland. bartoszg@amu.edu.pl.ORCID 0000-0003-1563-1262
Emerson CoyNanoBioMedical Centre, Adam Mickiewicz University, ul. Umultowska 85, PL-61614 Poznań, Poland. coyeme@amu.edu.pl.ORCID 0000-0002-4149-9720
Stefan JurgaNanoBioMedical Centre, Adam Mickiewicz University, ul. Umultowska 85, PL-61614 Poznań, Poland. stjurga@amu.edu.pl.
Radosław MrówczyńskiNanoBioMedical Centre, Adam Mickiewicz University, ul. Umultowska 85, PL-61614 Poznań, Poland. radoslaw.mrowczynski@amu.edu.pl.ORCID 0000-0003-3687-911X
Adam Mickiewicz University in Poznań · PL

Funding

Narodowe Centrum Badań i Rozwoju LIDER/11/0055/L-7/15/NCBiR/2016Narodowym Centrum Nauki 2016/21/B/ST8/00477
6 · The paper itself

Abstract

The growing incidence of cancer is a problem for modern medicine, since the therapeutic efficacy of applied modalities is still not satisfactory in terms of patients' survival rates, especially in the case of patients with brain tumors. The destructive influence of chemotherapy and radiotherapy on healthy cells reduces the chances of full recovery. With the development of nanotechnology, new ideas on cancer therapy, including brain tumors, have emerged. Photothermal therapy (PTT) is one of these. It utilizes nanoparticles (NPs) that can convert the light, preferably in the near-infrared (NIR) region, into heat. In this paper, we report the use of nanodiamonds (NDs) conjugated with biomimetic polydopamine (PDA) and indocyanine green (ICG) for glioblastoma cancer PTT therapy. The obtained materials were thoroughly analyzed in terms of their PTT effectiveness, as well as their physicochemical properties. The performed research demonstrated that NDs@PDA@ICG can be successfully applied in the photothermal therapy of glioblastoma for PTT and exhibited high photothermal conversion efficiency

Indexed as

cancer treatmentglioblastoma multiformeindocyanine greennanodiamondsphotothermal therapypolydopamine

Identifiers

PMID31105189
PMCPMC6477600
OpenAlexW2909280160

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.