Evidence map›Paper›PMID 31105181›Full record

ArticleBiomimetics (Basel, Switzerland)2017

Biomimetic Cationic Nanoparticles Based on Silica: Optimizing Bilayer Deposition from Lipid Films.

Rodrigo T Ribeiro, Victor H A Braga, Ana M Carmona-Ribeiro

Abstract read
In one paragraph

Article in Biomimetics (Basel, Switzerland), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Emerging Cationic Nanovaccines.Pharmaceutics · 2024
    Review
  2. Article
  3. Supramolecular Nanostructures for Vaccines.Biomimetics (Basel, Switzerland) · 2021
    Review
  4. Article
  5. Cationic Nanostructures for Vaccines Design.Biomimetics (Basel, Switzerland) · 2020
    Review
  6. Article
  7. Article
  8. Biosafety of Mesoporous Silica Nanoparticles.Biomimetics (Basel, Switzerland) · 2018
    Article
  9. Self-Assembled Antimicrobial Nanomaterials.International journal of environmental research and public health · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Rodrigo T RibeiroBiocolloids Laboratory, Instituto de Química, Universidade de São Paulo, Av. Lineu Prestes 748, São Paulo 05508-000, SP, Brazil. rodrigo@iq.usp.br.ORCID 0000-0002-5099-4256
Victor H A BragaBiocolloids Laboratory, Instituto de Química, Universidade de São Paulo, Av. Lineu Prestes 748, São Paulo 05508-000, SP, Brazil. victor.hugo.braga@usp.br.
Ana M Carmona-RibeiroBiocolloids Laboratory, Instituto de Química, Universidade de São Paulo, Av. Lineu Prestes 748, São Paulo 05508-000, SP, Brazil. amcr@usp.br.ORCID 0000-0001-8500-2707

Funding

Conselho Nacional de Desenvolvimento Científico e Tecnológico CNPq 302352/2014-7Universidade de São Paulo PUB-Benefício 83-1
6 · The paper itself

Abstract

The optimization of bilayer coverage on particles is important for a variety of biomedical applications, such as drug, vaccine, and genetic material delivery. This work aims at optimizing the deposition of cationic bilayers on silica over a range of experimental conditions for the intervening medium and two different assemblies for the cationic lipid, namely, lipid films or pre-formed lipid bilayer fragments. The lipid adsorption on silica in situ over a range of added lipid concentrations was determined from elemental analysis of carbon, hydrogen, and nitrogen and related to the colloidal stability, sizing, zeta potential, and polydispersity of the silica/lipid nanoparticles. Superior bilayer deposition took place from lipid films, whereas adsorption from pre-formed bilayer fragments yielded limiting adsorption below the levels expected for bilayer adsorption.

Indexed as

AEROSIL OX-50cationic bilayer fragmentscolloidal stabilitydioctadecyldimethylammonium bromideelemental analysis for in situ adsorptionfilms of cationic lipidsN-[1-(2,3-dioleoyloxy)propyl]-N,N,N-trimethylammonium chlorideoptimal bilayer adsorption from films

Identifiers

PMID31105181
PMCPMC6352667

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.