Evidence map›Paper›PMID 31105085›Full record

ArticleThe Journal of veterinary medical science2019

Spontaneous regression of canine papillomavirus type 2-related papillomatosis on footpads in a dog.

Keita Iyori, Kiyohiko Inai, Hidekatsu Shimakura, Takeshi Haga, Hiromi Shimoura, Ichiro Imanishi, Akihiro Imai, Toshiro Iwasaki

Open access · diamondAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of veterinary medical science, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 1 country.

Keita IyoriVet Derm Tokyo, Laboratory and Clinical Dermatology Services, 2-24-3, Kameido, Koto-ku, Tokyo 136-0071, Japan.
Kiyohiko InaiVet Derm Osaka, 2-3-55 Senbahigashi, Minoh, Osaka 562-0035, Japan.
Hidekatsu ShimakuraDivision of Infection Control and Disease Prevention, Graduate School of Agricultural and Life Sciences, The University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo 113-8657, Japan.
Takeshi HagaDivision of Infection Control and Disease Prevention, Graduate School of Agricultural and Life Sciences, The University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo 113-8657, Japan.
Hiromi ShimouraVet Derm Tokyo, Laboratory and Clinical Dermatology Services, 2-24-3, Kameido, Koto-ku, Tokyo 136-0071, Japan.
Ichiro ImanishiLaboratory of Veterinary Internal Medicine, Division of Animal Life Science, Graduate School, Tokyo University of Agriculture and Technology, 3-5-8 Saiwai-cho, Fuchu, Tokyo 183-8509, Japan.
Akihiro ImaiDermatology Service, Synergy Animal General Hospital, 815 Ishigami, Kawaguchi, Saitama 333-0823, Japan.
Toshiro IwasakiVet Derm Osaka, 2-3-55 Senbahigashi, Minoh, Osaka 562-0035, Japan.
Minoh City Hospital · JPThe University of Tokyo · JPKoto Hospital · JPNoguchi Hospital · JPTokyo University of Agriculture and Technology · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Persistent papillomatosis on footpads related to canine papillomavirus type 2 (CPV-2) infection has been described in dogs with immunocompromised condition. A 9-year-old, male French bulldog was presented with cauliflower-like nodules on the footpads of his left front leg. Histopathological examination revealed multiple finger-like projections of squamous epithelium with intranuclear inclusion bodies. Immunohistochemistry using an anti-bovine papillomavirus antibody demonstrated immunostaining in the keratinocytes. Partial genome DNA of CPV-2 was amplified from the lesion. Full genome sequence of CPV-2 in the subject showed 99.95% nucleotide identity with that of CPV-2 from the reference data. Two weeks after a biopsy, the skin lesion spontaneously regressed without any specific treatment. In non-immunocompromised dogs, CPV-2-related footpad papillomatosis could spontaneously resolve after a biopsy.

Indexed as

AnimalsBiopsyDNA, ViralDog DiseasesDogsKeratinocytesMalePapillomaPapillomaviridaeRemission, SpontaneousSkin NeoplasmsDNA, Viralcanine papillomavirus type 2footpad papillomatosisspontaneous regression

Identifiers

PMID31105085
PMCPMC6612484
OpenAlexW2945148358

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.