ReviewBiological psychiatry. Cognitive neuroscience and neuroimaging2019
Disrupted Corollary Discharge in Schizophrenia: Evidence From the Oculomotor System.
Review in Biological psychiatry. Cognitive neuroscience and neuroimaging, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07702526 (Effects of an Eye-Movement Intervention on Cognitive Impairment in Individuals Across Illness Stages of Schizophrenia), which is not on this map. Cited by 27 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effects of an Eye-Movement Intervention on Cognitive Impairment in Individuals Across Illness Stages of Schizophrenia: Protocol for a Stratified Randomized, Active-Controlled, Assessor-Blinded Trial
Who cites it
27 citing papers in PubMed.
- Associations between smooth pursuit, predictive pursuit, anomalous self-experiences, and psychotic-like experiences.European archives of psychiatry and clinical neuroscience · 2026Article
- A circuit dissection of perception-action decoupling in S-ketamine-induced hallucination-like states.Molecular psychiatry · 2026Article
- Corollary Discharge Dysfunction to Inner Speech and its Relationship to Auditory Verbal Hallucinations in Patients with Schizophrenia Spectrum Disorders.Schizophrenia bulletin · 2026Article
- Bodily Self-Disturbances and Hallucinations in Schizophrenia.Schizophrenia bulletin · 2025Review
- Multisensory integration of affective faces and voices in psychosis proneness.Schizophrenia (Heidelberg, Germany) · 2025Article
- Temporal characteristics of hemodynamic responses during active and passive hand movements in schizophrenia spectrum disorder.Schizophrenia (Heidelberg, Germany) · 2025Article
- Lawful kinematics link eye movements to the limits of high-speed perception.Nature communications · 2025Article
- Aberrant preparation of hand movement in schizophrenia spectrum disorder: an fMRI study.Brain communications · 2025Article
- Differing Pattern of Mismatch Negativity Responses in Clinical and Nonclinical Voice Hearers Challenge Predictive Coding Accounts of Psychosis.Biological psychiatry global open science · 2025Article
- Motor actions across psychiatric disorders: A research domain criteria (RDoC) perspective.Clinical psychology review · 2024Review
- Fixational eye movements and their associated evoked potentials during natural vision are altered in schizophrenia.Schizophrenia research. Cognition · 2024Article
- Abnormal Oculomotor Corollary Discharge Signaling as a Trans-diagnostic Mechanism of Psychosis.Schizophrenia bulletin · 2024Article
- Pre-saccadic shifts of attention in individuals diagnosed with schizophrenia.Brain and behavior · 2024Article
- Stronger tilt aftereffects in individuals diagnosed with schizophrenia spectrum disorders but not bipolar disorder.Schizophrenia research · 2024Article
- Article
- Working memory and sensory memory in subclinical high schizotypy: An avenue for understanding schizophrenia?The European journal of neuroscience · 2023Review
- Religious hallucinations in Lebanese patients with schizophrenia and their association with religious coping.BMC research notes · 2023Article
- Perceptual Functioning.Current topics in behavioral neurosciences · 2023Article
- Motor synchronization and impulsivity in pediatric borderline personality disorder with and without attention-deficit hyperactivity disorder: an eye-tracking study of saccade, blink and pupil behavior.Frontiers in neuroscience · 2023Article
- Consider the pons: bridging the gap on sensory prediction abnormalities in schizophrenia.Trends in neurosciences · 2022Review
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
Corollary discharge (CD) signals are motor-related signals that exert an influence on sensory processing. They allow mobile organisms to predict the sensory consequences of their imminent actions. Among the many functions of CD is to provide a means by which we can distinguish sensory experiences caused by our own actions from those with external causes. In this way, they contribute to a subjective sense of agency. A disruption in the sense of agency is central to many of the clinical symptoms of schizophrenia, and abnormalities in CD signaling have been theorized to underpin particularly those agency-related psychotic symptoms of the illness. Characterizing abnormal CD associated with eye movements in schizophrenia and their resulting influence on visual processing and subsequent action plans may have advantages over other sensory and motor systems. That is because the most robust psychophysiological and neurophysiological data regarding the dynamics and influence of CD as well as the neural circuitry implicated in CD generation and transmission comes from the study of eye movements in humans and nonhuman primates. We review studies of oculomotor CD signaling in the schizophrenia spectrum and possible neurobiological correlates of CD disturbances. We conclude by speculating on the ways in which oculomotor CD dysfunction, specifically, may invoke specific experiences, clinical symptoms, and cognitive impairments. These speculations lay the groundwork for empirical study, and we conclude by outlining potentially fruitful research directions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.