Evidence map›Paper›PMID 31104454›Full record

ArticleKorean journal of pediatrics2019

The role of Lactobacillus reuteri DSM 17938 for the absorption of iron preparations in children with iron deficiency anemia.

Jeanette Manoppo, Hilda Tasiringan, Audrey Wahani, Adrian Umboh, Max Mantik

Abstract read
In one paragraph

Article in Korean journal of pediatrics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
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  3. Article
  4. Review
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  6. Article
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  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jeanette ManoppoDivision of Gastroentero-hepatology, Department of Pediatrics, Sam Ratulangi University/Prof. Dr. R.D. Kandou Hospital Manado, Manado, Indonesia.
Hilda TasiringanDepartment of Pediatrics, Sam Ratulangi University/Prof. Dr. R.D. Kandou Hospital Manado, Manado, Indonesia.
Audrey WahaniDivision of Respirology, Department of Pediatrics, Sam Ratulangi University/ Prof. Dr. R.D. Kandou Hospital Manado, Manado, Indonesia.
Adrian UmbohDivision of Nephrology, Department of Pediatrics, Sam Ratulangi University/Prof. Dr. R.D. Kandou Hospital Manado, Manado, Indonesia.
Max MantikDivision of Hemato-Oncology, Department of Pediatrics, Sam Ratulangi University/Prof. Dr. R.D. Kandou Hospital Manado, Manado, Indonesia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo determine whether Lactobacillus reuteri DSM 17938 plays a role in absorption of iron preparations given to children with iron deficiency anemia (IDA).

methodsWe performed a quasi-experimental study involving pre- and postintervention tests using a control group in North Sulawesi province, Indonesia, between July and September 2017. We conducted a single-blind controlled trial that included primary school children who were diagnosed with IDA based on reticulocyte hemoglobin equivalent (Ret-He) levels <27.8 pg/L.

resultsA total of 66 children were randomized into 2 groups. Thirty-four children received iron preparations with the addition of L. reuteri DSM 17938 (group 1), whereas the other 32 received iron preparations alone (group 2). The baseline Ret-He levels before intervention were similar in both groups. After 14 days of intervention, mean Ret-He level in group 1 changed from 24.43±1.64 to 28.21±1.72 pg/ L (P=0.000). Mean Ret-He level in group 2 changed from 24.31±1.42 to 27.03±2.14 pg/L (P=0.000). Statistical analysis showed a significant increase in Ret-He levels in both groups; Ret-He levels were significantly higher in the experimental group than in the control group (P<0.05).

conclusionChildren with IDA receiving iron preparations with L. reuteri DSM 17938 for 14 days show higher Ret-He levels than those receiving iron preparations alone.

Indexed as

AnemiaChildIron deficiencyLactobacillus reuteri

Identifiers

PMID31104454
PMCPMC6528058

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.