Evidence map›Paper›PMID 31104273›Full record

ArticleMedical & biological engineering & computing2019

Regression based overall survival prediction of glioblastoma multiforme patients using a single discovery cohort of multi-institutional multi-channel MR images.

Parita Sanghani, Beng Ti Ang, Nicolas Kon Kam King, Hongliang Ren

Abstract read
PubMed Publisher
In one paragraph

Article in Medical & biological engineering & computing, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
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  4. Review
  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Parita SanghaniDepartment of Biomedical Engineering, National University of Singapore, Singapore, Singapore.
Beng Ti AngDepartment of Neurosurgery, National Neuroscience Institute, Singapore, Singapore.
Nicolas Kon Kam KingDepartment of Neurosurgery, National Neuroscience Institute, Singapore, Singapore.
Hongliang RenDepartment of Biomedical Engineering, National University of Singapore, Singapore, Singapore. ren@nus.edu.sg.ORCID http://orcid.org/0000-0002-6488-1551

Funding

NMRC Bedside Bench grant R-397-000-245-511Singapore Ministry of Health's National Medical Research Council NMRC/TCR/016-NNI/2016
6 · The paper itself

Abstract

Glioblastoma multiforme (GBM) are malignant brain tumors, associated with poor overall survival (OS). This study aims to predict OS of GBM patients (in days) using a regression framework and assess the impact of tumor shape features on OS prediction. Multi-channel MR image derived texture features, tumor shape, and volumetric features, and patient age were obtained for 163 GBM patients. In order to assess the impact of tumor shape features on OS prediction, two feature sets, with and without tumor shape features, were created. For the feature set with tumor shape features, the mean prediction error (MPE) was 14.6 days and its 95% confidence interval (CI) was 195.8 days. For the feature set excluding shape features, the MPE was 17.1 days and its 95% CI was observed to be 212.7 days. The coefficient of determination (R

Indexed as

Image Processing, Computer-AssistedBrain NeoplasmsDatabases, FactualGlioblastomaHumansImaging, Three-DimensionalMagnetic Resonance ImagingRegression AnalysisGlioblastoma multiformeMachine learningOverall survival predictionShape featuresSupport vector regression

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.