ArticleEnvironmental science and pollution research international2019
Ameliorative effect of Spirulina platensis against lead nitrate-induced cytotoxicity and genotoxicity in catfish Clarias gariepinus.
Article in Environmental science and pollution research international, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 57 citations in OpenAlex.
- Protective role of probiotics or Spirulina platensis supplementation against mercury-induced hematological, histopathological, and antioxidant-immune gene dysregulation in Nile Tilapia (Oreochromis niloticus).Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2026Article
- Phycochemistry and pharmacological significance of filamentous cyanobacterium Spirulina sp.Bioresources and bioprocessing · 2025Review
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- Deleterious effects of polypropylene released from paper cups on blood profile and liver tissue ofFrontiers in physiology · 2024Article
- The synergetic effects of 4-nonylphenol and polyethylene microplastics in Cyprinus carpio juveniles using blood biomarkers.Scientific reports · 2023Article
- The mitigating effect of Spirulina (Arthrospira platensis) on the hemotoxicity of gibberellic acid on juvenile tilapia (Oreochromis niloticus).Environmental science and pollution research international · 2023Article
- Toxicity of co-exposure of microplastics and lead in African catfish (Frontiers in veterinary science · 2023Article
- Investigating the effects of copper sulfate and copper oxide nanoparticles in Nile tilapia (Oreochromis niloticus) using multiple biomarkers: the prophylactic role of Spirulina.Environmental science and pollution research international · 2021Article
- Microplastics-Induced Eryptosis and Poikilocytosis in Early-Juvenile Nile Tilapia (Frontiers in physiology · 2021Article
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- The protective role of spirulina and β-glucan in African catfish (Clarias gariepinus) against chronic toxicity of chlorpyrifos: hemato-biochemistry, histopathology, and oxidative stress traits.Environmental science and pollution research international · 2020Article
- Hemotoxic effects of some herbicides on juvenile of Nile tilapia Oreochromis niloticus.Environmental science and pollution research international · 2019Article
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Corrections and comments
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Authors and funding
3 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The present study was designed to investigate the protective role of dietary supplementation of Spirulina platensis (SP) against cytotoxic and genotoxic effects of lead nitrate in Clarias gariepinus. Four groups of fishes were used: first group as control which fed on basal diet, second group fed on basal diet and exposed to (1 mg/L of lead nitrate), third group fed on diet containing 0.25% SP and exposed to (1 mg/L of lead nitrate), and fourth group fed on diet containing 0.5%SP and exposed to (1 mg/L of lead nitrate). Fish samples were taken at 2nd and 4th week of exposure. The hematological indices of lead nitrate-exposed group were decreased significantly compared to the control group at 2nd and 4th week of exposure. Lead nitrate caused a significant increase in the percentage of poikilocytosis, micronuclei, and apoptotic cells as well as comet tail length and olive tail moment compared with the control group at 2nd and 4th week of exposure. The highest level of damage was found on 4th week of exposure with all parameters. Dietary inclusion of SP ameliorated these cytotoxic and genetic changes, as well as this amelioration was concentration and time dependent. Consequently, the present study proposed that the addition of SP to the fish diet can be used as a promising protective agent to oppose cytotoxic and genotoxic effects of lead nitrate in aquaculture. Graphical abstract.
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