Evidence map›Paper›PMID 31104205›Full record

ReviewCurrent cardiology reports2019

Novel Myocardial PET/CT Receptor Imaging and Potential Therapeutic Targets.

Ines Valenta, Pal Pacher, Vasken Dilsizian, Thomas H Schindler

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current cardiology reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Radiotracers for Molecular Imaging of Angiotensin-Converting Enzyme 2.International journal of molecular sciences · 2024
    Review
  2. Review
  3. Cardiac hybrid imaging: novel tracers for novel targets.Journal of geriatric cardiology : JGC · 2021
    Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 1 country.

Ines ValentaMallinckrodt Institute of Radiology, Division of Nuclear Medicine, Washington University School of Medicine, Washington University in St. Louis, 510 S. Kingshighway Boulevard, Campus Box 8223, St. Louis, MO, 63110, USA.
Pal PacherLaboratory of Physiological Studies, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, MD, USA.
Vasken DilsizianDepartment of Diagnostic Radiology and Nuclear Medicine, The University of Maryland School of Medicine, Baltimore, MD, USA.
Thomas H SchindlerMallinckrodt Institute of Radiology, Division of Nuclear Medicine, Washington University School of Medicine, Washington University in St. Louis, 510 S. Kingshighway Boulevard, Campus Box 8223, St. Louis, MO, 63110, USA. thschindler@wustl.edu.
Mallinckrodt (United States) · USNational Institutes of Health · USUniversity of Maryland, Baltimore · USWashington University in St. Louis · US

Funding

Mechanism of oxidative/nitrosative stress and inflammation-induced tissue injuryZIAAA000375 · NIAAA · NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM · PI PACHER, PAL · 2009 to 2025
$27.8M
6 · The paper itself

Abstract

purpose of the reviewActivation of myocardial cannabinoid type 1 receptors (CB1-R) and/or angiotensin II type 1 receptors (AT1-R) likely plays an important mechanistic role in determining the left-ventricular remodeling process in systolic heart failure. We provide an overview on novel radiotracer probes and positron emission tomography (PET)/computed tomography (CT) imaging to noninvasively probe the expression of myocardial CB1-R and/or AT1-R. RECENT

findingsRecent translational investigations have demonstrated the feasibility of

Indexed as

HeartHeart FailureHumansMyocardiumPositron Emission Tomography Computed TomographyRadiopharmaceuticalsReceptor, Angiotensin, Type 1Receptors, CannabinoidVentricular Dysfunction, LeftVentricular RemodelingRadiopharmaceuticalsReceptor, Angiotensin, Type 1Receptors, CannabinoidAngiotensin-converting enzymeAngiotensin II type 1 receptorsCannabinoid type 1 receptorHeart failureLeft-ventricular remodelingObesityPositron emission tomography

Identifiers

PMID31104205
OpenAlexW2946308775

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.