ArticleJournal of gastroenterology2019
Preceding endoscopic submucosal dissection for T1 colorectal carcinoma does not affect the prognosis of patients who underwent additional surgery: a large multicenter propensity score-matched analysis.
Article in Journal of gastroenterology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
32 citing papers in PubMed, 2 syntheses or guidelines pooled it, 62 citations in OpenAlex.
- Endoscopic resection versus surgery for T1 rectal cancer: A systematic review and meta-analysis of oncologic and safety outcomes.Surgical endoscopy · 2026Pooled it
- Prior endoscopic resection does not affect the outcome of secondary surgery for T1 colorectal cancer, a systematic review and meta-analysis.International journal of colorectal disease · 2022Pooled it
- Prediction of lymph node metastasis in early colorectal cancer based on histologic images by artificial intelligence.Scientific reports · 2022Trial
- Predictive factors for isolated pulmonary metastasis in pathological T1 colorectal cancer following curative resection with lymph node dissection: a multicenter study.Surgery today · 2026Article
- Article
- Surveillance and Surgical Salvage Treatment for Endoscopically Removed T1 Colorectal Cancers.Gut and liver · 2025Review
- Vessel invasion is a risk factor for gastric cancer: a retrospective analysis study.World journal of surgical oncology · 2024Article
- Resection of Early Colorectal Neoplasms Using Endoscopic Submucosal Dissection: A Retrospective Multicenter Cohort Study.Journal of clinical medicine · 2024Article
- Lymphovascular invasion is a dominant risk factor for lymph node metastasis in T2 rectal cancer.Endoscopy international open · 2024Article
- Endoscopic Mucosal Resection and Endoscopic Submucosal Dissection.Clinics in colon and rectal surgery · 2024Review
- Vertical margin distance in T1 colorectal carcinoma resected by endoscopic submucosal dissection affects prognosis after additional surgery.International journal of colorectal disease · 2024Article
- Article
- Completion Surgery after Non-Curative Local Resection of Early Rectal Cancer.Visceral medicine · 2024Review
- A new clinical model for predicting lymph node metastasis in T1 colorectal cancer.International journal of colorectal disease · 2024Article
- Diagnostic and therapeutic strategies for colorectal tumor with positive muscle-retracting sign.DEN open · 2024Article
- Comparative prediction of lymph node metastasis in pT1 colorectal cancer among Western and Japanese guidelines.Frontiers in oncology · 2024Article
- Weighing the benefits of lymphadenectomy in early-stage colorectal cancer.Annals of surgical treatment and research · 2023Review
- Outcome of Completion Surgery after Endoscopic Submucosal Dissection in Early-Stage Colorectal Cancer Patients.Cancers · 2023Article
- Effects of prior endoscopic resection on recurrence in patients with T1 colorectal cancer who underwent radical surgery.International journal of colorectal disease · 2023Article
- Long-term outcomes after endoscopic versus surgical resection of T1 colorectal carcinoma.Surgical endoscopy · 2023Article
Corrections and comments
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Authors and funding
16 authors at 9 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundWe analyzed the influence of preceding endoscopic submucosal dissection (ESD) on the prognosis of patients with T1 colorectal carcinoma (CRC) after additional surgery using propensity-score matching.
methods1638 consecutive patients with T1 CRC were retrospectively identified between January 1998 and December 2016 at the Hiroshima GI Endoscopy Research Group. We assessed 602 patients with 602 T1 CRC who underwent additional surgery after ESD (n = 216) or surgery alone (n = 386). The enrolled patients were treated according to the Japanese Society for Cancer of the Colon and Rectum (JSCCR) guidelines 2016, and were defined as non-endoscopically curable (non-e-curable) when they did not satisfy its curative criteria. We analyzed the pathological characteristics and the prognosis of non-e-curable patients using propensity-score matching between the additional surgery after ESD and surgery alone groups.
resultsThere were no cases of recurrence and lymph node metastasis among the e-curable patients. The rate of lymph node metastasis and recurrences in the non-e-curable patients were 10.8% and 2.6%, respectively. After propensity-score matching, there were no significant differences in the 5-year overall survival rates (96.9% vs. 92.0%), 5-year disease-free survival rates (96.7% vs. 96.7%) and 5-year disease-specific survival rates (100% vs. 98.6%) after treatment of T1 CRCs between the 2 groups in non-e-curable patients.
conclusionsPreceding ESD with histological en bloc resection for patients with T1 CRC did not affect their oncologic behavior adversely after additional surgery.
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