ArticleNeuroImage. Clinical2019
Functional plasticity of the ipsilateral primary sensorimotor cortex in an elite long jumper with below-knee amputation.
Article in NeuroImage. Clinical, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
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Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.
- Oscillatory dynamics of motor learning across adulthood life span: a systematic review.Frontiers in aging neuroscience · 2025Pooled it
- Acute hemoglobin responses during bench press exercise across relative loads and sport backgrounds: a cross-sectional functional near-infrared spectroscopy study.European journal of applied physiology · 2026Article
- Electromyographic activity during bench press differs by attentional focus strategy and sport: a cross-sectional comparison of bodybuilding, powerlifting, and paralympic powerlifting.European journal of applied physiology · 2026Article
- Optimizing exercise for brain health: cortical activation and connectivity across different exercise modalities.Brain structure & function · 2026Article
- Functional-Structural Plasticity Associated With the Duration of Sports Participation in Lower Limb Amputees: A Multimodal Neuroimaging Study.Neural plasticity · 2026Article
- Specific recruitment properties of spinal reflex of thigh muscle in sprinter.Scientific reports · 2025Article
- The Neuroplastic Outcomes from Impaired Sensory Expectations (NOISE) hypothesis: How ACL dysfunction impacts sensory perception and knee stability.Musculoskeletal science & practice · 2025Review
- Phantom limb syndrome: from pathogenesis to treatment. A narrative review.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2024Review
- Agonist-antagonist myoneural interface amputation preserves proprioceptive sensorimotor neurophysiology in lower limbs.Science translational medicine · 2020Article
- "Paralympic Brain". Compensation and Reorganization of a Damaged Human Brain with Intensive Physical Training.Sports (Basel, Switzerland) · 2020Article
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Functional plasticity of the sensorimotor cortex occurs following motor practice, as well as after limb amputation. However, the joint effect of limb amputation and intensive, long-term motor practice on cortical plasticity remains unclear. Here, we recorded brain activity during unilateral contraction of the hip, knee, and ankle joint muscles from a long jump Paralympic gold medalist with a unilateral below-knee amputation (Amputee Long Jumper, ALJ). He used the amputated leg with a prosthesis for take-off. Under similar conditions to the ALJ, we also recorded brain activity from healthy long jumpers (HLJ) and non-athletes with a below-knee amputation. During a rhythmic isometric contraction of knee extensor muscles with the take-off/prosthetic leg, the ALJ activated not only the contralateral primary sensorimotor cortex (M1/S1), but also the ipsilateral M1/S1. In addition, this ipsilateral M1/S1 activation was significantly greater than that seen in the HLJ. However, we did not find any significant differences between the ALJ and HLJ in M1/S1 activation during knee muscle contraction in the non-take-off/intact leg, nor during hip muscle contraction on either side. Region of interest analysis revealed that the ALJ exhibited a greater difference in M1/S1 activity and activated areas ipsilateral to the movement side between the take-off/prosthetic and non-take-off/intact legs during knee muscle contraction compared with the other two groups. However, difference in activity in M1/S1 contralateral to the movement side did not differ across groups. These results suggest that a combination of below-knee amputation and intensive, prolonged long jump training using a prosthesis (i.e. fine knee joint control) induced an expansion of the functional representation of the take-off/prosthetic leg in the ipsilateral M1/S1 in a muscle-specific manner. These results provide novel insights into the potential for substantial cortical plasticity with an extensive motor rehabilitation program.
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