Evidence map›Paper›PMID 31103650›Full record

ArticleThe American journal of medicine2019

Leisure-Time Running Reduces the Risk of Incident Type 2 Diabetes.

Yuehan Wang, Duck-Chul Lee, Angelique G Brellenthin, Thijs M H Eijsvogels, Xuemei Sui, Timothy S Church, Carl J Lavie, Steven N Blair

Abstract read
In one paragraph

Article in The American journal of medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 2 pooled it
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 31 citations in OpenAlex.

  1. Pooled it
  2. American Association of Clinical Endocrinology Clinical Practice Guideline: Developing a Diabetes Mellitus Comprehensive Care Plan-2022 Update.Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists · 2022
    Guideline
  3. Review
  4. Review
  5. Environmental Preferences and Concerns of Recreational Trail Runners.International journal of environmental research and public health · 2024
    Article
  6. Review
  7. Time Spent Jogging/Running and Biological Aging in 4458 U.S. Adults: An NHANES Investigation.International journal of environmental research and public health · 2023
    Article
  8. Article
  9. Article
  10. Review
  11. Correlation between Cardiopulmonary Indices and Running Performance in a 14.5 km Endurance Running Event.International journal of environmental research and public health · 2022
    Article
  12. Article
  13. Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 2 countries.

Yuehan WangDepartment of Kinesiology, Iowa State University, Ames, IA; Department of Physiology, Radboud University Medical Center, Nijmegen, The Netherlands.
Duck-Chul LeeDepartment of Kinesiology, Iowa State University, Ames, IA. Electronic address: dclee@iastate.edu.
Angelique G BrellenthinDepartment of Kinesiology, Iowa State University, Ames, IA.
Thijs M H EijsvogelsDepartment of Physiology, Radboud University Medical Center, Nijmegen, The Netherlands.
Xuemei SuiDepartment of Exercise Science, University of South Carolina, Columbia, SC.
Timothy S ChurchDepartment of Preventive Medicine, Pennington Biomedical Research Center, Baton Rouge, LA.
Carl J LavieDepartment of Cardiovascular Diseases, John Ochsner Heart and Vascular Institute, Ochsner Clinical School, University of Queensland School of Medicine, New Orleans, LA.
Steven N BlairDepartment of Exercise Science, University of South Carolina, Columbia, SC.
Iowa State University · USUniversity of South Carolina · USPennington Biomedical Research Center · USRadboud University Medical Center · NLRadboud University Nijmegen · NL

Funding

Comparison of the Cardiovascular Benefits of Resistance, Aerobic, and Combined Exercise (Cardio-RACE)R01HL133069 · NHLBI · IOWA STATE UNIVERSITY · PI LEE, DUCK-CHUL · 2016 to 2020
$3.4M
Impact of Physical Fitness and Exercise on HealthR37AG006945 · NIA · COOPER INSTITUTE · PI BLAIR, STEVEN N. · 2002 to 2005
$2.7M
CORONARY ARTERY CALCIUM, EXERCISE TESTS, AND CHD OUTCOMER01HL062508 · NHLBI · COOPER INSTITUTE · PI LAMONTE, MICHAEL J · 1999 to 2004
$2.5M
IMPACT OF PHYSICAL FITNESS &EXERCISE ON HEALTHR01AG006945 · NIA · COOPER INSTITUTE · PI BLAIR, STEVEN N. · 1986 to 2001
$1.1M
Understanding Patterns of Change in Obesity and Physical Activity in AdultsR21DK088195 · NIDDK · UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA · PI SUI, XUEMEI · 2010 to 2011
$397k
NHLBI NIH HHS R01 HL062508NHLBI NIH HHS R01 HL133069NIA NIH HHS R01 AG006945NIA NIH HHS R37 AG006945NIDDK NIH HHS R21 DK088195
6 · The paper itself

Abstract

objectivesWe examined the overall association as well as the dose-response relationship between leisure-time running and incident type 2 diabetes.

methodsParticipants were 19,347 adults aged 18-100 years who were free of cardiovascular disease, cancer, and diabetes at baseline, and who received at least 2 extensive preventive medical examinations between 1974 and 2006. Running and other types of aerobic physical activity were assessed by self-reported leisure-time activities. Type 2 diabetes was defined as fasting glucose ≥126 mg/dL (7.0 mmol/L), physician diagnosis, or insulin use.

resultsDuring an average follow-up of 6.5 years, 1015 adults developed type 2 diabetes. Approximately 29.5% of adults participated in leisure-time running at baseline. Runners had a 28% (hazard ratio [HR] 0.72; 95% confidence interval [CI], 0.62-0.84) lower risk of developing type 2 diabetes compared with nonrunners during follow-up. The HRs (95% CIs) of type 2 diabetes were 0.98 (0.75-1.28), 0.69 (0.51-0.92), 0.62 (0.45-0.85), 0.78 (0.59-1.04), and 0.57 (0.42-0.79) across quintiles of running time (minutes/week) compared with nonrunners after adjusting for potential confounders, including levels of nonrunning aerobic physical activity. Similar dose-response relationships between running distance (miles/week), frequency (times/week), total amount (MET-minutes/week), and speed (mph) were also observed.

conclusionsParticipating in leisure-time running is associated with a lower risk of developing type 2 diabetes in adults. Consistent linear dose-response relationships were observed between various running parameters and incident type 2 diabetes, supporting the prescription of running to prevent type 2 diabetes.

Indexed as

AdolescentAdultAgedAged, 80 and overDiabetes Mellitus, Type 2FemaleHumansLeisure ActivitiesMaleMiddle AgedRisk AssessmentRisk FactorsRunningAerobic exerciseCohortRunningType 2 diabetes

Identifiers

PMID31103650
PMCPMC6832784
OpenAlexW2945182897

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.