Evidence map›Paper›PMID 31103562›Full record

ArticleJournal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus2019

Binocular amblyopia treatment with contrast-rebalanced movies.

Eileen E Birch, Reed M Jost, Angie De La Cruz, Krista R Kelly, Cynthia L Beauchamp, Lori Dao, David Stager, Joel N Leffler

2 registry-linked trialsOpen access · greenAbstract read
In one paragraph

Article in Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 39 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed, 2 pooled it
5.3field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04315649 nacompletednot on this mapstarted 2021, after this paper: background citation

Effect of 3D Movie Viewing on Stereopsis in Strabismus and / or Anisometropic Amblyops

TypeinterventionalSponsorUniversitat Politècnica de CatalunyaRan2021 to 2022Enrolled24ConditionsAmblyopia, Anisometropic Amblyopia, Strabismic AmblyopiaArms3D movie viewing
NCT06150391 naunknown statusnot on this mapstarted 2023, after this paper: background citation

Randomized Controlled Trial of a Dichoptic Gabor Videogame Program to Improve Visual Function in Children With Amblyopia

TypeinterventionalSponsorHospital de MeridaRan2023 to 2024Enrolled120ConditionsAmblyopiaArmsVisionary: computer exercises using dichoptic Gabor Patches and band-filtered noise masks, Patching
3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 2 syntheses or guidelines pooled it, 66 citations in OpenAlex.

  1. Pooled it
  2. Guideline
  3. Patch-free streaming contrast-rebalanced dichoptic cartoons versus patching for treatment of amblyopia in children aged 3 to 5 years: a pilot, randomized clinical trial.Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus · 2024
    Trial
  4. Trial
  5. Barriers to successful dichoptic treatment for amblyopia in young children.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2021
    Trial
  6. A pilot randomized trial of contrast-rebalanced binocular treatment for deprivation amblyopia.Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus · 2020
    Trial
  7. A randomized clinical trial of contrast increment protocols for binocular amblyopia treatment.Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus · 2020
    Trial
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Baseline and outcome stereoacuity of children with anisometropic amblyopia undergoing dichoptic amblyopia treatment.Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus · 2025
    Article
  15. Article
  16. Review
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Eileen E BirchRetina Foundation of the Southwest, Dallas, Texas; UT Southwestern Medical Center, Dallas, Texas. Electronic address: ebirch@rfsw.org.
Reed M JostRetina Foundation of the Southwest, Dallas, Texas.
Angie De La CruzRetina Foundation of the Southwest, Dallas, Texas.
Krista R KellyRetina Foundation of the Southwest, Dallas, Texas.
Cynthia L BeauchampABC Eyes, Dallas, Texas.
Lori DaoABC Eyes, Dallas, Texas.
David StagerPediatric Ophthalmology & Adult Strabismus, Plano, Texas.
Joel N LefflerChildren's Eye Care of North Texas, Plano, Texas.
Retina Foundation of the Southwest · USAdult and Pediatric Dermatology · USSouthwestern Medical Center

Funding

Binocular Vision, Amblyopia, and Refractive Development in EsotropiaR01EY022313 · NEI · RETINA FOUNDATION OF THE SOUTHWEST · PI Eileen Elizabeth Birch · 2012 to 2026
$7.0M
NEI NIH HHS R01 EY022313
6 · The paper itself

Abstract

backgroundBinocular amblyopia treatments promote visual acuity recovery and binocularity by rebalancing the signal strength of dichoptic images. Most require active participation by the amblyopic child to play a game or perform a repetitive visual task. The purpose of this study was to investigate a passive form of binocular treatment with contrast-rebalanced dichoptic movies.

methodsA total of 27 amblyopic children, 4-10 years of age, wore polarized glasses to watch 6 contrast-rebalanced dichoptic movies on a passive 3D display during a 2-week period. Amblyopic eye contrast was 100%; fellow eye contrast was initially set to a lower level (20%-60%), which allowed the child to overcome suppression and use binocular vision. Fellow eye contrast was incremented by 10% for each subsequent movie. Best-corrected visual acuity, random dot stereoacuity, and interocular suppression were measured at baseline and at 2 weeks.

resultsAmblyopic eye best-corrected visual acuity improved from 0.57 ± 0.22 at baseline to 0.42 ± 0.23 logMAR (t

conclusionsIn this cohort, passive viewing of contrast-rebalanced dichoptic movies effectively improved visual acuity in amblyopic subjects. The degree of improvement observed was similar to that previously reported for 2 weeks of binocular games treatment and with 3-4 months of occlusion therapy.

Indexed as

Computers, HandheldMotion PicturesVideo GamesVisual AcuityAmblyopiaChildChild, PreschoolEyeglassesFemaleFollow-Up StudiesHumansMaleRefraction, OcularRetrospective StudiesVision, Binocular

Identifiers

PMID31103562
PMCPMC6698207
OpenAlexW2945863954

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.