Evidence map›Paper›PMID 31103457›Full record

ArticleThe Journal of allergy and clinical immunology2019

Combined immunodeficiency in a patient with c-Rel deficiency.

Sarah Beaussant-Cohen, Faris Jaber, Michel J Massaad, Sabrina Weeks, Jennifer Jones, Mohammed F Alosaimi, Jacqueline Wallace, Waleed Al-Herz, Raif S Geha, Janet Chou

Abstract readCase ReportsLetter
In one paragraph

Article in The Journal of allergy and clinical immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

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  20. Regulation of B-cell function by NF-kappaB c-Rel in health and disease.Cellular and molecular life sciences : CMLS · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Sarah Beaussant-CohenDivision of Immunology, Boston Children's Hospital, Harvard Medical School, Boston, Mass.
Faris JaberDivision of Immunology, Boston Children's Hospital, Harvard Medical School, Boston, Mass.
Michel J MassaadDivision of Immunology, Boston Children's Hospital, Harvard Medical School, Boston, Mass.
Sabrina WeeksDivision of Immunology, Boston Children's Hospital, Harvard Medical School, Boston, Mass.
Jennifer JonesDivision of Immunology, Boston Children's Hospital, Harvard Medical School, Boston, Mass.
Mohammed F AlosaimiDivision of Immunology, Boston Children's Hospital, Harvard Medical School, Boston, Mass; Department of Pediatrics, King Saud University, Riyadh, Saudi Arabia.
Jacqueline WallaceDivision of Immunology, Boston Children's Hospital, Harvard Medical School, Boston, Mass.
Waleed Al-HerzDepartment of Pediatrics, Faculty of Medicine, Kuwait University, and Allergy and Clinical Immunology Unit, Department of Pediatrics, Al-Sabah Hospital, Kuwait City, Kuwait.
Raif S GehaDivision of Immunology, Boston Children's Hospital, Harvard Medical School, Boston, Mass.
Janet ChouDivision of Immunology, Boston Children's Hospital, Harvard Medical School, Boston, Mass. Electronic address: Janet.Chou@childrens.harvard.edu.

Funding

MOLECULAR BASIS OF ALLERGIC AND IMMUNOLOGIC DISEASET32AI007512 · NIAID · CHILDREN'S HOSPITAL BOSTON · PI Janet Chou, Peter A Nigrovic · 1996 to 2026
$13.1M
Mechanisms of a Novel Combined Immunodeficiency Caused by a Homozygous Mutation in COPG1R01AI139633 · NIAID · BOSTON CHILDREN'S HOSPITAL · PI GEHA, RAIF SALIM · 2018 to 2022
$3.1M
Novel mechanisms of T cell costimulation: the role of LRRC8A in T cell activationK08AI116979 · NIAID · BOSTON CHILDREN'S HOSPITAL · PI CHOU, JANET · 2015 to 2019
$934k
NIAID NIH HHS K08 AI116979NIAID NIH HHS R01 AI139633NIAID NIH HHS T32 AI007512
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

ChildChild, PreschoolHumansMaleProto-Oncogene Proteins c-relSevere Combined ImmunodeficiencyProto-Oncogene Proteins c-relREL protein, human

Identifiers

PMID31103457
PMCPMC6688935

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.