Evidence map›Paper›PMID 31103225›Full record

ArticleBiophysical journal2019

Mechanical Properties of Chondrocytes Estimated from Different Models of Micropipette Aspiration.

Yongsheng Li, Yueqin Li, Quanyou Zhang, Lili Wang, Meiqing Guo, Xiaogang Wu, Yuan Guo, Jing Chen, Weiyi Chen

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biophysical journal, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yongsheng LiInstitute of Applied Mechanics, College of Mechanical and Vehicle Engineering, Taiyuan University of Technology, Taiyuan, China.
Yueqin LiShanxi Dayi Hospital, Taiyuan, China; Shanxi Academy of Medical Sciences, Taiyuan, China.
Quanyou ZhangInstitute of Biomedical Engineering, College of Biomedical Engineering, Taiyuan University of Technology, Taiyuan, China.
Lili WangInstitute of Biomedical Engineering, College of Biomedical Engineering, Taiyuan University of Technology, Taiyuan, China.
Meiqing GuoInstitute of Applied Mechanics, College of Mechanical and Vehicle Engineering, Taiyuan University of Technology, Taiyuan, China.
Xiaogang WuInstitute of Biomedical Engineering, College of Biomedical Engineering, Taiyuan University of Technology, Taiyuan, China.
Yuan GuoInstitute of Biomedical Engineering, College of Biomedical Engineering, Taiyuan University of Technology, Taiyuan, China.
Jing ChenInstitute of Biomedical Engineering, College of Biomedical Engineering, Taiyuan University of Technology, Taiyuan, China. Electronic address: 1165059779@qq.com.
Weiyi ChenInstitute of Biomedical Engineering, College of Biomedical Engineering, Taiyuan University of Technology, Taiyuan, China. Electronic address: 819903@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this study, two viscoelastic creep expressions for the aspirated length of individual solid-like cells undergoing micropipette aspiration (MPA) were derived based on our previous studies wherein the cell size relative to the micropipette and the cell compressibility were taken into account. Next, three mechanical models of MPA, the half-space model (HSM), incompressible sphere model (ICSM), and compressible sphere model (CSM), were employed to fit the MPA data of chondrocytes. The results indicated that the elastic moduli and viscoelastic parameters of chondrocytes for the ICSM and CSM exhibited significantly higher values than those from the HSM (p < 0.001) because of the considerations of the geometric parameter (ξ) and the compressibility of the cell (ν). For the normal chondrocytes, the elastic moduli obtained from the ICSM and CSM (ν = 0.3) were 47.4 and 78.9% higher than those from the HSM. In the viscoelasticity, the parameters k

Indexed as

Mechanical PhenomenaModels, BiologicalBiomechanical PhenomenaChondrocytesMicrotechnology

Identifiers

PMID31103225
PMCPMC6554473

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.