Evidence map›Paper›PMID 31103181›Full record

ReviewThe Veterinary clinics of North America. Food animal practice2019

Postnatal Nutrient Repartitioning due to Adaptive Developmental Programming.

Robert J Posont, Dustin T Yates

Open access · greenAbstract readReview
In one paragraph

Review in The Veterinary clinics of North America. Food animal practice, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
4.0field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Robert J PosontDepartment of Animal Science, University of Nebraska-Lincoln, PO Box 830908, Lincoln, NE 68583, USA.
Dustin T YatesDepartment of Animal Science, University of Nebraska-Lincoln, PO Box 830908, Lincoln, NE 68583, USA. Electronic address: dustin.yates@unl.edu.
University of Nebraska–Lincoln · US

Funding

The role of stress in the fetal origin of obesity and metabolic dysfunctionP20GM104320 · NIGMS · UNIVERSITY OF NEBRASKA LINCOLN · PI ZEMPLENI, JANOS · 2014 to 2024
$24.9M
NIGMS NIH HHS P20 GM104320
6 · The paper itself

Abstract

Fetal stress induces developmental adaptations that result in intrauterine growth restriction (IUGR) and low birthweight. These adaptations reappropriate nutrients to the most essential tissues, which benefits fetal survival. The same adaptations are detrimental to growth efficiency and carcass value in livestock, however, because muscle is disproportionally targeted. IUGR adipocytes, liver tissues, and pancreatic β-cells also exhibit functional adaptations. Identifying mechanisms underlying adaptive changes is fundamental to improving outcomes and value in low birthweight livestock. The article outlines studies that have begun to identify stress-induced fetal adaptations affecting growth, metabolism, and differential nutrient utilization in IUGR-born animals.

Indexed as

Adaptation, PhysiologicalAnimal HusbandryAnimalsFemaleFetal Growth RetardationHumansLivestockNutrientsPregnancyPrenatal Nutritional Physiological PhenomenaNutrientsDevelopmental origins of health and diseaseFetal adaptationsFetal stressNutrient repartitioningThrifty phenotype

Identifiers

PMID31103181
PMCPMC6527338
OpenAlexW2945344244

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.