Evidence map›Paper›PMID 31103066›Full record

ArticlePlacenta2019

The Placental Atlas Tool (PAT): A collaborative research and discovery platform for the placental research community.

John V Ilekis, Michael Keller, Alexandra Shlionskaya, Christopher H Ferguson, Bianca Patel, Alexander Lobkovsky Meitiv, Bryan Gorman, Archana Mohale

Abstract read
In one paragraph

Article in Placenta, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

John V IlekisEunice Kennedy Shriver National Institute of Child Health and Human Development, Pregnancy and Perinatology Branch, Bethesda, MD, 20817, USA. Electronic address: ilekisj@nih.gov.
Michael KellerBooz Allen Hamilton, Inc., McLean, Virginia, 22102, USA.
Alexandra ShlionskayaBooz Allen Hamilton, Inc., McLean, Virginia, 22102, USA.
Christopher H FergusonBooz Allen Hamilton, Inc., McLean, Virginia, 22102, USA.
Bianca PatelBooz Allen Hamilton, Inc., McLean, Virginia, 22102, USA.
Alexander Lobkovsky MeitivBooz Allen Hamilton, Inc., McLean, Virginia, 22102, USA.
Bryan GormanBooz Allen Hamilton, Inc., McLean, Virginia, 22102, USA.
Archana MohaleEunice Kennedy Shriver National Institute of Child Health and Human Development, Information Resources Management Branch, Bethesda, MD, 20817, USA.

Funding

Intramural NIH HHS Z99 HD999999
6 · The paper itself

Abstract

introductionThe placenta is one of the least understood, yet arguably one of the most important organs for human health and development. While there have been numerous research efforts dedicated to understanding the placenta's critical role, these studies and the data they produced remain separated and largely disparate. In order to facilitate placental research, the Eunice Kennedy Shriver National Institute of Child and Human Development (NICHD) released in October 2018 the Placental Atlas Tool (PAT) (https://pat.nichd.nih.gov/), an internet-based platform offering users a centralized placental database of molecular datasets, analytic tools, and images.

methodsPAT is a cloud-based system developed by the business requirements defined by NICHD leadership and extramural placental researchers. PAT employs a metadata-driven web interface to provide curated placental datasets and images, enriched with structured, descriptive metadata to enhance data discoverability. PAT also incorporates open source molecular data analytical tools to provide a flexible analytics workflow for placental researchers.

resultsPAT launched with 426 analyzable molecular placental datasets consisting of over 12,500 samples from 10 distinct species, all systematically annotated and processed for enhanced research utility. 828 placental images, consisting of 7 imaging modalities across 47 species, and nearly 300 annotated linked publications supplement the datasets to facilitate knowledge integration and hypothesis generation across disparate molecular studies. DISCUSSION: PAT will maximize the NICHD's investment in placental research by reinforcing open scientific inquiry, facilitating reuse of datasets, promoting novel research and testing of new hypotheses and analytic methods, and facilitating education of new researchers.

Indexed as

Atlases as TopicDatabases, FactualPlacentaAnimalsFemaleHumansPregnancyAtlasBioinformaticsPlacentaResourceSoftware

Identifiers

PMID31103066
PMCPMC6527124

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.