Evidence map›Paper›PMID 31102238›Full record

ArticleNeurocritical care2019

Definition and Prioritization of Data Elements for Cohort Studies and Clinical Trials on Patients with Unruptured Intracranial Aneurysms: Proposal of a Multidisciplinary Research Group.

Katharina A M Hackenberg, Ale Algra, Rustam Al-Shahi Salman, Juhana Frösen, David Hasan, Seppo Juvela, David Langer, Philip Meyers, Akio Morita, Gabriel Rinkel and 2 more

Erratum issuedAbstract readConsensus Development Conference, NIH
PubMed Publisher
In one paragraph

Article in Neurocritical care, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors.

Katharina A M HackenbergDepartment of Neurosurgery, University Hospital Mannheim, University of Heidelberg, Mannheim, Germany. katharina.hackenberg@umm.de.ORCID http://orcid.org/0000-0003-0548-9936
Ale AlgraBrain Center Rudolph Magnus, Department of Neurology and Neurosurgery, and the Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands.
Rustam Al-Shahi SalmanCentre for Clinical Brain Sciences, University of Edinburgh, Chancellor's Building, Edinburgh, UK.
Juhana FrösenDepartment of Neurosurgery, Kuopio University Hospital, Kuopio, Finland.
David HasanDepartment of Neurosurgery, University of Iowa Carver College of Medicine, Iowa City, IA, USA.
Seppo JuvelaDepartment of Clinical Neurosciences, University of Helsinki, Helsinki, Finland.
David LangerDepartment of Neurosurgery, Hofstra Northwell School of Medicine, and Northwell Health, Lenox-Hill Hospital, New York, NY, USA.
Philip MeyersDepartments of Neurosurgery and Radiology, Columbia University Medical Center, New York, NY, USA.
Akio MoritaDepartment of Neurological Surgery, Nippon Medical School, Bunkyo-ku, Tokyo, Japan.
Gabriel Rinkel *Brain Center Rudolf Magnus, Department of Neurology and Neurosurgery and Center of Excellence for Rehabilitation Medicine, University Medical Center Utrecht, Utrecht, The Netherlands.
Nima Etminan *Department of Neurosurgery, University Hospital Mannheim, University of Heidelberg, Mannheim, Germany.
Unruptured Aneurysms and SAH CDE Project Investigators

Funding

Medical Research Council G1002605Medical Research Council G108/613NINDS NIH HHS HHSN271201200034C
6 · The paper itself

Abstract

introductionVariability in usage and definition of data characteristics in previous cohort studies on unruptured intracranial aneurysms (UIA) complicated pooling and proper interpretation of these data. The aim of the National Institute of Health/National Institute of Neurological Disorders and Stroke UIA and Subarachnoid Hemorrhage (SAH) Common Data Elements (CDE) Project was to provide a common structure for data collection in future research on UIA and SAH.

methodsThis paper describes the development and summarization of the recommendations of the working groups (WGs) on UIAs, which consisted of an international and multidisciplinary panel of cerebrovascular specialists on research and treatment of UIAs. Consensus recommendations were developed by review of previously published CDEs for other neurological diseases and the literature on UIAs. Recommendations for CDEs were classified by priority into 'Core,' 'Supplemental-Highly Recommended,' 'Supplemental,' and 'Exploratory.'

resultsNinety-one CDEs were compiled; 69 were newly created and 22 were existing CDEs. The CDEs were assigned to eight subcategories and were classified as Core (8), Supplemental-Highly Recommended (23), Supplemental (25), and Exploratory (35) elements. Additionally, the WG developed and agreed on a classification for aneurysm morphology.

conclusionThe proposed CDEs have been distilled from a broad pool of characteristics, measures, or outcomes. The usage of these CDEs will facilitate pooling of data from cohort studies or clinical trials on patients with UIAs.

Indexed as

Common Data ElementsIntracranial AneurysmBiomedical ResearchClinical Trials as TopicCohort StudiesHumansNational Institute of Neurological Disorders and Stroke (U.S.)National Library of Medicine (U.S.)United StatesCommon data elementsData standardizationMorphologyRisk factorsUnruptured intracranial aneurysms

Identifiers

PMID31102238

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.