Evidence map›Paper›PMID 31102198›Full record

ReviewBiophysical reviews2019

Inorganic nanomaterials for chemo/photothermal therapy: a promising horizon on effective cancer treatment.

Mona Khafaji, Masoud Zamani, Mortaza Golizadeh, Omid Bavi

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Biophysical reviews, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed.

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  12. NdMaterials (Basel, Switzerland) · 2024
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  17. CuFeSACS applied materials & interfaces · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Mona KhafajiDepartment of Chemistry, Sharif University of Technology, Tehran, Iran. mona.khafaji@gmail.com.
Masoud ZamaniInstitute for Biotechnology and Environment (IBE), Sharif University of Technology, Tehran, Iran.
Mortaza GolizadehInstitute for Biotechnology and Environment (IBE), Sharif University of Technology, Tehran, Iran.
Omid BaviDepartment of Mechanical and Aerospace Engineering, Shiraz University of Technology, Shiraz, Iran. o.bavi@sutech.ac.ir.ORCID http://orcid.org/0000-0003-3539-0849

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

During the last few decades, nanotechnology has established many essential applications in the biomedical field and in particular for cancer therapy. Not only can nanodelivery systems address the shortcomings of conventional chemotherapy such as limited stability, non-specific biodistribution and targeting, poor water solubility, low therapeutic indices, and severe toxic side effects, but some of them can also provide simultaneous combination of therapies and diagnostics. Among the various therapies, the combination of chemo- and photothermal therapy (CT-PTT) has demonstrated synergistic therapeutic efficacies with minimal side effects in several preclinical studies. In this regard, inorganic nanostructures have been of special interest for CT-PTT, owing to their high thermal conversion efficiency, application in bio-imaging, versatility, and ease of synthesis and surface modification. In addition to being used as the first type of CT-PTT agents, they also include the most novel CT-PTT systems as the potentials of new inorganic nanomaterials are being more and more discovered. Considering the variety of inorganic nanostructures introduced for CT-PTT applications, enormous effort is needed to perform translational research on the most promising nanomaterials and to comprehensively evaluate the potentials of newly introduced ones in preclinical studies. This review provides an overview of most novel strategies used to employ inorganic nanostructures for cancer CT-PTT as well as cancer imaging and discusses current challenges and future perspectives in this area.

Indexed as

Chemo/Photothermal therapyGold-based nanomaterialsIron- based nanomaterialsMetal Sulfiedbased nanomaterials

Identifiers

PMID31102198
PMCPMC6557961

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.